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- W2309920250 abstract "Abstract The randomized controlled trials (RCTs) of breast cancer screening were conducted 20–50 years in the past. Since that time, such critical factors as women’s risk, screening technology, and breast cancer treatment have all evolved. This makes us less certain that we can trust the RCTs to inform decision makers of the benefits and harms of screening in today’s world. Because of several important inherent problems of RCTs, many have turned to observational studies to provide evidence relevant to the current day. Unfortunately, observational studies also have important limitations that make us question their results. There are ways, however, to improve the validity and reliability of observational studies. An international team of independent experts should develop standards for trustworthy observational studies of screening that can then be carried out in an ongoing way to monitor the benefits and harms of screening." @default.
- W2309920250 created "2016-06-24" @default.
- W2309920250 creator A5036643072 @default.
- W2309920250 date "2016-01-01" @default.
- W2309920250 modified "2023-09-26" @default.
- W2309920250 title "The Importance of Observational Evidence to Estimate and Monitor Mortality Reduction From Current Breast Cancer Screening" @default.
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- W2309920250 doi "https://doi.org/10.1016/b978-0-12-802209-2.00004-8" @default.
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