Matches in SemOpenAlex for { <https://semopenalex.org/work/W2310712741> ?p ?o ?g. }
- W2310712741 endingPage "66" @default.
- W2310712741 startingPage "51" @default.
- W2310712741 abstract "Hydrogels hold a macromolecular structure comparable to that of native tissues and thus are very attractive materials for tissue engineering. The authors prepared three-dimensional bioartificial matrices based on methacrylated gelatin and chondroitin sulfate that can be tuned to closely mimic the natural environment of specific cell types – for example, chondrocytes. The authors investigated the hydrogel’s gel yield, swellability, mechanical strength, cytocompatibility, degradation and effect on chondrocyte redifferentiation. Furthermore, porcine chondrocytes were photoencapsulated into hydrogels and cultivated for 21 d. It was found that the methacrylation of chondroitin sulfate is crucial for the generation of stable hydrogels with methacrylated gelatin. Compared to pure gelatin, hybrid hydrogels possessed significantly higher swellability, while the mechanical strength remained constant. The hydrogel properties could be controlled by the mass fraction and the cross-linking density. The hydrogels as well as the cross-linking conditions were proven to render cytocompatible. Furthermore, it was found that the addition of chondroitin sulfate promoted a spherical morphology and thus chondrocyte phenotype retention. Thus, it is suggested that chondroitin sulfate is a potential redifferentiating agent of articular chondrocytes. In summary, hydrogels based on both chondroitin sulfate and gelatin hold tunable physical and biological properties and are preferable matrices for cartilage tissue engineering." @default.
- W2310712741 created "2016-06-24" @default.
- W2310712741 creator A5011854683 @default.
- W2310712741 creator A5026949751 @default.
- W2310712741 creator A5090358331 @default.
- W2310712741 date "2016-06-01" @default.
- W2310712741 modified "2023-09-26" @default.
- W2310712741 title "Biopolymer-based hydrogels for cartilage tissue engineering" @default.
- W2310712741 cites W1592939385 @default.
- W2310712741 cites W1907406329 @default.
- W2310712741 cites W192031638 @default.
- W2310712741 cites W1958939387 @default.
- W2310712741 cites W1967269017 @default.
- W2310712741 cites W1972287513 @default.
- W2310712741 cites W1973031436 @default.
- W2310712741 cites W1976842528 @default.
- W2310712741 cites W1979644915 @default.
- W2310712741 cites W1980253140 @default.
- W2310712741 cites W1985140092 @default.
- W2310712741 cites W1986233240 @default.
- W2310712741 cites W1993680967 @default.
- W2310712741 cites W2003731025 @default.
- W2310712741 cites W2012058521 @default.
- W2310712741 cites W2012320747 @default.
- W2310712741 cites W2018376286 @default.
- W2310712741 cites W2018617685 @default.
- W2310712741 cites W2022106720 @default.
- W2310712741 cites W2024533065 @default.
- W2310712741 cites W2028981877 @default.
- W2310712741 cites W2032209750 @default.
- W2310712741 cites W2043358786 @default.
- W2310712741 cites W2045037817 @default.
- W2310712741 cites W2049411403 @default.
- W2310712741 cites W2051920559 @default.
- W2310712741 cites W2064769928 @default.
- W2310712741 cites W2068114077 @default.
- W2310712741 cites W2069537082 @default.
- W2310712741 cites W2070050615 @default.
- W2310712741 cites W2070206697 @default.
- W2310712741 cites W2071583928 @default.
- W2310712741 cites W2073259535 @default.
- W2310712741 cites W2073854293 @default.
- W2310712741 cites W2076355487 @default.
- W2310712741 cites W2076612949 @default.
- W2310712741 cites W2077443558 @default.
- W2310712741 cites W2082718250 @default.
- W2310712741 cites W2084610464 @default.
- W2310712741 cites W2088824573 @default.
- W2310712741 cites W2089567262 @default.
- W2310712741 cites W2090221779 @default.
- W2310712741 cites W2093573945 @default.
- W2310712741 cites W2097122410 @default.
- W2310712741 cites W2110052568 @default.
- W2310712741 cites W2118614307 @default.
- W2310712741 cites W2120948303 @default.
- W2310712741 cites W2126111746 @default.
- W2310712741 cites W2127229759 @default.
- W2310712741 cites W2128208163 @default.
- W2310712741 cites W2130257778 @default.
- W2310712741 cites W2134413691 @default.
- W2310712741 cites W2141219094 @default.
- W2310712741 cites W2142162781 @default.
- W2310712741 cites W2143953113 @default.
- W2310712741 cites W2157010935 @default.
- W2310712741 cites W2159185781 @default.
- W2310712741 cites W2159542600 @default.
- W2310712741 cites W2161824899 @default.
- W2310712741 cites W2163084598 @default.
- W2310712741 cites W2163149880 @default.
- W2310712741 cites W2164613644 @default.
- W2310712741 cites W2164880987 @default.
- W2310712741 cites W2165227294 @default.
- W2310712741 cites W2165569726 @default.
- W2310712741 cites W4205677429 @default.
- W2310712741 cites W4244240406 @default.
- W2310712741 cites W4244523227 @default.
- W2310712741 cites W4246108954 @default.
- W2310712741 cites W4296979652 @default.
- W2310712741 doi "https://doi.org/10.1680/jbibn.15.00017" @default.
- W2310712741 hasPublicationYear "2016" @default.
- W2310712741 type Work @default.
- W2310712741 sameAs 2310712741 @default.
- W2310712741 citedByCount "20" @default.
- W2310712741 countsByYear W23107127412016 @default.
- W2310712741 countsByYear W23107127412017 @default.
- W2310712741 countsByYear W23107127412018 @default.
- W2310712741 countsByYear W23107127412019 @default.
- W2310712741 countsByYear W23107127412020 @default.
- W2310712741 countsByYear W23107127412022 @default.
- W2310712741 crossrefType "journal-article" @default.
- W2310712741 hasAuthorship W2310712741A5011854683 @default.
- W2310712741 hasAuthorship W2310712741A5026949751 @default.
- W2310712741 hasAuthorship W2310712741A5090358331 @default.
- W2310712741 hasConcept C105702510 @default.
- W2310712741 hasConcept C108586683 @default.
- W2310712741 hasConcept C12554922 @default.
- W2310712741 hasConcept C127413603 @default.
- W2310712741 hasConcept C136229726 @default.