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- W2310882212 abstract "A number of findings and postulates concerning the etiology and development of squamous carcinoma of the cervix are presented. Colposcopy and associated laboratory study of the cervix in more than 14000 females of all ages and reproductive statuses elucidated the important phases of the natural history of squamous metaplasia. Coitus itself may play a part in the etiology of carcinoma of the cervix the disease seeming to be a venereal disease of sorts. Extrinsic deoxyribonucleic acid in the form of virus acting as a biological mutagen may be present in semen. The periods of early adolescence and first pregnancy seem most vulnerable to extrinsic factors of coital origin. Though at first consideration a coital factor would seem to necessitate a more common incidence of the disease the relative infrequency could be explained by 1) loss of chance of combination of environmental nucleic acid with host cell nucleic acid for various reasons 2) neoplastic transformation being but 1 and an uncommon result of the mutation process and 3) successful operation of immune mechanisms against the neoplastic epithelium." @default.
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- W2310882212 date "1968-09-01" @default.
- W2310882212 modified "2023-09-27" @default.
- W2310882212 title "The etiology of squamous carcinoma of the cervix." @default.
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