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- W2310914331 abstract "Commentary on: Tahar R, Almelli T, Debue C, et al. Randomized trial of artesunate-amodiaquine, atovaquone-proguanil, and artesunate-atovaquone-proguanil for the treatment of uncomplicated falciparum malaria in children. J Infect Dis 2014;210:1962–71.[OpenUrl][1][Abstract/FREE Full Text][2] Artemisinin-based combination therapies (ACTs) are the treatment of choice for uncomplicated Plasmodium falciparum malaria in malaria endemic countries. ACT resistance has already been documented in the main, but not solely in Asia,1 therefore therapeutic alternatives should be investigated. As there are no new drugs at advance stages in the pipeline, current focus should be on novel combinations of existing drugs. This prospective randomised study compares the effectiveness of three antimalaria combination drugs—two well-established combination drugs (artesunate-amodiaquine (AA) and atovaquone-proguanil (AP)) and one … [1]: {openurl}?query=rft.jtitle%253DJ%2BInfect%2BDis%26rft_id%253Dinfo%253Adoi%252F10.1093%252Finfdis%252Fjiu341%26rft_id%253Dinfo%253Apmid%252F24943722%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=jinfdis&resid=210/12/1962&atom=%2Febmed%2F21%2F2%2F64.atom" @default.
- W2310914331 created "2016-06-24" @default.
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- W2310914331 date "2016-01-12" @default.
- W2310914331 modified "2023-09-27" @default.
- W2310914331 title "Artemisinin-based combination therapy (ACT) versus atovaquone-proguanil: do not choose between but, rather, combine them" @default.
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- W2310914331 doi "https://doi.org/10.1136/ebmed-2015-110183" @default.
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