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- W2312303169 abstract "II. Case description A 5 year old female child presented with cough, cold, fast breathing and drooling of saliva. Child was born out of non consanguineous marriage, without any perinatal insult during delivery or developmental delay. No history of sibling death or autoimmune disorders in the family. On examination, there was ptosis (Figure 1) which was more significant during the late in the evening and other neurological and systemic examination was unremarkable. Ophthalmological examination was done revealed ptosis without any gaze evoked nystagmus. Routine blood investigations were within normal limits. With progressive ptosis towards the end of the day, Juvenile Myasthenia gravis was suspected. Acetyl cholinesterase (AcHE) test was done with subcutaneous injection of neostigmine which showed a dramatic response (Figure 2). Repetitive nerve stimulation RNS study showed significant decremental response (>10%) in orbicularis oculi, Right and Left trapezius muscle, suggestive of post synaptic neuromuscular junction (NMJ) receptor disorder. Computerized tomography CT scan of thorax was done to rule out thymic hyperplasia. We diagnosed this child as a case of juvenile myasthenia gravis and treated with pyridostigmine. The child improved symptomatically and under the follow up (Figure 3)." @default.
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- W2312303169 date "2014-01-01" @default.
- W2312303169 modified "2023-10-04" @default.
- W2312303169 title "Juvenile myasthenia gravis" @default.
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- W2312303169 doi "https://doi.org/10.9790/0853-131054041" @default.
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