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• W2312537237 abstract "Colorectal cancer continues to be a major cause of significant morbidity and mortality in the United States. Approximately 140,000 American men and women will be newly diagnosed with colorectal cancer this year, and approximately 45,000 will die of this disease. 17 An asymptomatic, average-risk individual's lifetime risk of developing colorectal cancer is about 6%.Colorectal cancer develops from premalignant adenomatous polyps (adenomas). Colonoscopy offers a complete examination of the entire colon and rectum, during which benign adenomas can be identified and removed before they have the opportunity to progress to cancer. In addition, early-stage cancers can be detected prior to local progression or distant metastatic spread. The 5-year survival rates for an early-stage Dukes A cancer range from 80% to 90%.Screening tests for colorectal cancer are performed to identify asymptomatic individuals in the general population who, by finding a positive result on the screening test, are likely to have a colorectal neoplasm, such as a premalignant adenoma or an invasive cancer. In contrast, follow-up surveillance examinations are performed periodically on individuals already at increased risk, such as those with a prior diagnosis of a colorectal neoplasm or a history of chronic inflammatory bowel disease. This article will review guidelines for colorectal cancer screening and surveillance in average-risk and high-risk individuals with a personal or family history of colorectal polyps or cancer, chronic colitis, and inherited syndromes." @default.
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• W2312537237 date "1980-11-01" @default.
• W2312537237 modified "2023-09-27" @default.
• W2312537237 title "A Practical Approach to the Risk of Cancer in Inflammatory Bowel Disease: Reassure, Watch, or Act?" @default.
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• W2312537237 doi "https://doi.org/10.1016/s0025-7125(16)31564-4" @default.
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