FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2312729197> ?p ?o ?g. }

• W2312729197 endingPage "165" @default.
• W2312729197 startingPage "157" @default.
• W2312729197 abstract "Traumatic injury remains a major cause of morbidity and mortality worldwide, and patients who survived the initial insult are susceptible to an overwhelming inflammatory dysfunction that will lead to acute coagulopathy of trauma (ACOT) and subsequently multiple organ dysfunction syndrome (MODS). Multiple organ dysfunction syndrome–related scoring systems, although they measure organ dysfunction, present clinical markers, and single-cytokine estimates are unable to predict accurately the events of MODS in the clinical setting to aid risk stratification. In this study, a pig model comprising the lethal triad of trauma was used to determine prognostic patterns of early circulating trauma markers so as to predict the development of MODS and ACOT. We measured early expression of several biomarkers (neutrophil gelatinase–associated protein, high-mobility group box 1, C-reactive protein, tumor necrosis factor-α, heart-type fatty acid binding protein, and D-dimers) and clinical parameters for various organ injuries and abnormalities (creatinine, creatine kinase myocardial band, aspartate aminotransferase, and maximum clot firmness) at later time points. The strength of association between the early expression of several biomarkers to the development of MODS and ACOT in polytraumatized pigs was tested using the Spearman correlation coefficient. These biomarkers were found useful to predict the onset of renal, cardiac, hepatic, and hemostatic abnormalities. The findings show that these biomarkers could help to identify, guide, and streamline damage control surgery and earlier intervention to reverse the detrimental outcomes of MODS and ACOT." @default.
• W2312729197 created "2016-06-24" @default.
• W2312729197 creator A5002809166 @default.
• W2312729197 creator A5005363273 @default.
• W2312729197 creator A5014693062 @default.
• W2312729197 creator A5016796082 @default.
• W2312729197 creator A5020870791 @default.
• W2312729197 creator A5029696998 @default.
• W2312729197 creator A5038495908 @default.
• W2312729197 creator A5076535790 @default.
• W2312729197 date "2015-02-01" @default.
• W2312729197 modified "2023-09-26" @default.
• W2312729197 title "Potential Biomarker Panel for Predicting Organ Dysfunction and Acute Coagulopathy in a Polytrauma Porcine Model" @default.
• W2312729197 cites W1585870092 @default.
• W2312729197 cites W168035116 @default.
• W2312729197 cites W1863224167 @default.
• W2312729197 cites W1969249603 @default.
• W2312729197 cites W1973561333 @default.
• W2312729197 cites W1992034786 @default.
• W2312729197 cites W2005399274 @default.
• W2312729197 cites W2005674294 @default.
• W2312729197 cites W2010366574 @default.
• W2312729197 cites W2018586741 @default.
• W2312729197 cites W2023047307 @default.
• W2312729197 cites W2027888996 @default.
• W2312729197 cites W2044410575 @default.
• W2312729197 cites W2048778797 @default.
• W2312729197 cites W2051686352 @default.
• W2312729197 cites W2061863854 @default.
• W2312729197 cites W2083820537 @default.
• W2312729197 cites W2094327837 @default.
• W2312729197 cites W2116886160 @default.
• W2312729197 cites W2129351461 @default.
• W2312729197 cites W2143394454 @default.
• W2312729197 cites W2146653354 @default.
• W2312729197 cites W2148879334 @default.
• W2312729197 doi "https://doi.org/10.1097/shk.0000000000000279" @default.
• W2312729197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25347751" @default.
• W2312729197 hasPublicationYear "2015" @default.
• W2312729197 type Work @default.
• W2312729197 sameAs 2312729197 @default.
• W2312729197 citedByCount "13" @default.
• W2312729197 countsByYear W23127291972015 @default.
• W2312729197 countsByYear W23127291972016 @default.
• W2312729197 countsByYear W23127291972018 @default.
• W2312729197 countsByYear W23127291972020 @default.
• W2312729197 countsByYear W23127291972022 @default.
• W2312729197 crossrefType "journal-article" @default.
• W2312729197 hasAuthorship W2312729197A5002809166 @default.
• W2312729197 hasAuthorship W2312729197A5005363273 @default.
• W2312729197 hasAuthorship W2312729197A5014693062 @default.
• W2312729197 hasAuthorship W2312729197A5016796082 @default.
• W2312729197 hasAuthorship W2312729197A5020870791 @default.
• W2312729197 hasAuthorship W2312729197A5029696998 @default.
• W2312729197 hasAuthorship W2312729197A5038495908 @default.
• W2312729197 hasAuthorship W2312729197A5076535790 @default.
• W2312729197 hasBestOaLocation W23127291971 @default.
• W2312729197 hasConcept C10936531 @default.
• W2312729197 hasConcept C126322002 @default.
• W2312729197 hasConcept C141071460 @default.
• W2312729197 hasConcept C142724271 @default.
• W2312729197 hasConcept C2776692886 @default.
• W2312729197 hasConcept C2778384902 @default.
• W2312729197 hasConcept C2778426790 @default.
• W2312729197 hasConcept C2779936836 @default.
• W2312729197 hasConcept C2780306776 @default.
• W2312729197 hasConcept C2780472472 @default.
• W2312729197 hasConcept C2780835948 @default.
• W2312729197 hasConcept C2781090800 @default.
• W2312729197 hasConcept C2781197716 @default.
• W2312729197 hasConcept C55493867 @default.
• W2312729197 hasConcept C60644358 @default.
• W2312729197 hasConcept C71924100 @default.
• W2312729197 hasConcept C86803240 @default.
• W2312729197 hasConcept C90924648 @default.
• W2312729197 hasConceptScore W2312729197C10936531 @default.
• W2312729197 hasConceptScore W2312729197C126322002 @default.
• W2312729197 hasConceptScore W2312729197C141071460 @default.
• W2312729197 hasConceptScore W2312729197C142724271 @default.
• W2312729197 hasConceptScore W2312729197C2776692886 @default.
• W2312729197 hasConceptScore W2312729197C2778384902 @default.
• W2312729197 hasConceptScore W2312729197C2778426790 @default.
• W2312729197 hasConceptScore W2312729197C2779936836 @default.
• W2312729197 hasConceptScore W2312729197C2780306776 @default.
• W2312729197 hasConceptScore W2312729197C2780472472 @default.
• W2312729197 hasConceptScore W2312729197C2780835948 @default.
• W2312729197 hasConceptScore W2312729197C2781090800 @default.
• W2312729197 hasConceptScore W2312729197C2781197716 @default.
• W2312729197 hasConceptScore W2312729197C55493867 @default.
• W2312729197 hasConceptScore W2312729197C60644358 @default.
• W2312729197 hasConceptScore W2312729197C71924100 @default.
• W2312729197 hasConceptScore W2312729197C86803240 @default.
• W2312729197 hasConceptScore W2312729197C90924648 @default.
• W2312729197 hasIssue "2" @default.
• W2312729197 hasLocation W23127291971 @default.
• W2312729197 hasLocation W23127291972 @default.
• W2312729197 hasOpenAccess W2312729197 @default.
• W2312729197 hasPrimaryLocation W23127291971 @default.

• next