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- W2312777468 abstract "We compared apheresis products collected by two cell separators (Spectra and CS3000) for peripheral blood stem cell harvest (PBSCH), the total number of 110 apheresis procedures were done in 46 patients, who underwent two or three procedures over consecutive days. Respective results for apheresis products collected by Spectra and CS3000 were as follows (mean±standard deviation): whole white cells (×109), 16.2 (±14.0) and 11.1 (±9.15); mononuclear cells (×109), 9.21 (±6.59) and 7.74 (±6.12); CD34-positive cells (×108), 3.20 (±6.49) and 2.06 (±3.78); and CFU-GM (×105), 381 (±687) and 252 (±398). Thus, the ratio of mononuclear cells harvested using CS3000 was higher than that by Spectra (76% vs 68%, p<0.05). Although the ratio of CD34-positive cells was equal between the two products, a greater number of stem cells (CD34-positive cells and CFU-GM) was harvested with Spectra than CS3000 (p<0.05).These results showed that the purity of mononuclear cells harvested by CS3000 is superior to that by Spectra. However, Spectra was able to collect peripheral stem cells more efficiently." @default.
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- W2312777468 date "1996-01-01" @default.
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- W2312777468 title "Comparison of the apheresis products collected by two cell separators (Spectra and CS3000) for peripheral blood stem cell harvest." @default.
- W2312777468 doi "https://doi.org/10.3925/jjtc1958.42.279" @default.
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