Matches in SemOpenAlex for { <https://semopenalex.org/work/W2312842016> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2312842016 endingPage "875" @default.
- W2312842016 startingPage "871" @default.
- W2312842016 abstract "Primary hyperparathyroidism (PHPT) is often associated with low bone mineral density (BMD). An open-labeled, prospective trial was conducted to determine whether alendronate (ALN), 10 mg daily, maintains or improves BMD in patients with advanced PHPT. All patients had symptomatic PHPT and met surgical guidelines however refused surgery. Nineteen patients was treated with alendronate for 2 years. The primary outcome index, BMD, was measured at the lumbar spine (LS) and femoral neck (FN) every 6 months by dual-energy x-ray absorptiometry. Serum calcium, phosphorous and PTH, and urinary calcium excretion were monitored every 3 months. Treatment with alendronate over 2 years was associated with a significant (5.3+/-0.4%; p<0.01) increase in LS BMD in comparison with baseline. FN BMD increased significantly at 24 months with alendronate by 2.5%+/-0.7 (p<0.01) from baseline. Serum calcium, phosphorus and PTH, and urine calcium excretion did not change with alendronate therapy. In PHPT, alendronate significantly increases BMD at the LS and FN at 24 months from baseline values with stable serum calcium and PTH levels. Alendronate may be a useful alternative to parathyroidectomy in symptomatic PHPT among those with low BMD, who are candidates for surgery but either decline or for whom surgery is contraindicated." @default.
- W2312842016 created "2016-06-24" @default.
- W2312842016 creator A5045554018 @default.
- W2312842016 date "2005-11-01" @default.
- W2312842016 modified "2023-09-27" @default.
- W2312842016 title "Alendronate increases bone mineral density in patients with symptomatic primary hyperparathyroidism" @default.
- W2312842016 cites W1970517193 @default.
- W2312842016 cites W1988558749 @default.
- W2312842016 cites W2004906281 @default.
- W2312842016 cites W2013599591 @default.
- W2312842016 cites W2016622147 @default.
- W2312842016 cites W2021561859 @default.
- W2312842016 cites W2039156201 @default.
- W2312842016 cites W2058077355 @default.
- W2312842016 cites W2064584518 @default.
- W2312842016 cites W2066449183 @default.
- W2312842016 cites W2081056468 @default.
- W2312842016 cites W2082385085 @default.
- W2312842016 cites W2088244676 @default.
- W2312842016 cites W2093820271 @default.
- W2312842016 cites W2113108574 @default.
- W2312842016 cites W2117165995 @default.
- W2312842016 cites W2141096951 @default.
- W2312842016 cites W2313541363 @default.
- W2312842016 cites W238753812 @default.
- W2312842016 cites W2463618578 @default.
- W2312842016 cites W3023624733 @default.
- W2312842016 cites W1966674735 @default.
- W2312842016 cites W2320972218 @default.
- W2312842016 cites W2402479502 @default.
- W2312842016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16821204" @default.
- W2312842016 hasPublicationYear "2005" @default.
- W2312842016 type Work @default.
- W2312842016 sameAs 2312842016 @default.
- W2312842016 citedByCount "1" @default.
- W2312842016 countsByYear W23128420162016 @default.
- W2312842016 crossrefType "journal-article" @default.
- W2312842016 hasAuthorship W2312842016A5045554018 @default.
- W2312842016 hasConcept C126322002 @default.
- W2312842016 hasConcept C126894567 @default.
- W2312842016 hasConcept C141071460 @default.
- W2312842016 hasConcept C2775854910 @default.
- W2312842016 hasConcept C2775945674 @default.
- W2312842016 hasConcept C2776541429 @default.
- W2312842016 hasConcept C2776697488 @default.
- W2312842016 hasConcept C2776886416 @default.
- W2312842016 hasConcept C2777645128 @default.
- W2312842016 hasConcept C2779053571 @default.
- W2312842016 hasConcept C2781208988 @default.
- W2312842016 hasConcept C519063684 @default.
- W2312842016 hasConcept C71924100 @default.
- W2312842016 hasConceptScore W2312842016C126322002 @default.
- W2312842016 hasConceptScore W2312842016C126894567 @default.
- W2312842016 hasConceptScore W2312842016C141071460 @default.
- W2312842016 hasConceptScore W2312842016C2775854910 @default.
- W2312842016 hasConceptScore W2312842016C2775945674 @default.
- W2312842016 hasConceptScore W2312842016C2776541429 @default.
- W2312842016 hasConceptScore W2312842016C2776697488 @default.
- W2312842016 hasConceptScore W2312842016C2776886416 @default.
- W2312842016 hasConceptScore W2312842016C2777645128 @default.
- W2312842016 hasConceptScore W2312842016C2779053571 @default.
- W2312842016 hasConceptScore W2312842016C2781208988 @default.
- W2312842016 hasConceptScore W2312842016C519063684 @default.
- W2312842016 hasConceptScore W2312842016C71924100 @default.
- W2312842016 hasIssue "6" @default.
- W2312842016 hasLocation W23128420161 @default.
- W2312842016 hasLocation W23128420162 @default.
- W2312842016 hasOpenAccess W2312842016 @default.
- W2312842016 hasPrimaryLocation W23128420161 @default.
- W2312842016 hasRelatedWork W132109910 @default.
- W2312842016 hasRelatedWork W1497204631 @default.
- W2312842016 hasRelatedWork W1579581312 @default.
- W2312842016 hasRelatedWork W1663455607 @default.
- W2312842016 hasRelatedWork W1965974344 @default.
- W2312842016 hasRelatedWork W1979685329 @default.
- W2312842016 hasRelatedWork W1980060473 @default.
- W2312842016 hasRelatedWork W2016622147 @default.
- W2312842016 hasRelatedWork W2036257783 @default.
- W2312842016 hasRelatedWork W2083530338 @default.
- W2312842016 hasRelatedWork W2126750245 @default.
- W2312842016 hasRelatedWork W2145408269 @default.
- W2312842016 hasRelatedWork W2171017921 @default.
- W2312842016 hasRelatedWork W2323434348 @default.
- W2312842016 hasRelatedWork W2350849736 @default.
- W2312842016 hasRelatedWork W2357460119 @default.
- W2312842016 hasRelatedWork W2407048049 @default.
- W2312842016 hasRelatedWork W2411030716 @default.
- W2312842016 hasRelatedWork W3023624733 @default.
- W2312842016 hasRelatedWork W3047735199 @default.
- W2312842016 hasVolume "56" @default.
- W2312842016 isParatext "false" @default.
- W2312842016 isRetracted "false" @default.
- W2312842016 magId "2312842016" @default.
- W2312842016 workType "article" @default.