FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2312969522> ?p ?o ?g. }

• W2312969522 abstract "Background: Dyspepsia and heartburn are among the most frequent complaints of the upper gastrointestinal tract impacting quality of life. The present study aimed to investigate the impact of drinking a natural mineral water (medicinal product category “Heilwasser” in Germany) high in hydrogen carbonate (Staatl. Fachingen STILL) on functional dyspeptic complaints and heartburn. Methods: 56 men and women with self-reported heartburn were enrolled to this one-arm pilot study. They had to drink 1.5 L of a hydrogen carbonate rich mineral water each day over a course of six weeks. Participants reported the number and duration of heartburn episodes in a daily dairy. The Reflux Disease Questionnaire (RDQ), Quality of Life in Reflux and Dyspepsia questionnaire (QOLRAD) and the Gastrointestinal Quality of Life Index (GILQI) were used to assess the therapeutic course of the treatment and the Short Form Health Survey (SF-12) to assess general quality of life. Mean ± standard deviation were calculated and pre- and post-treatment changes were compared using the Wilcoxon test. Results: The consumption of a hydrogen carbonate rich mineral water decreased the number of heartburn episodes per week significantly by 4.8 ± 8.2 at the end of the study (p < 0.001). The duration of episodes was also significantly reduced by 25.7 minutes after six weeks of intervention (p < 0.001). Accordingly, the subjectively perceived severity of heartburn, regurgitation and dyspeptic complaints as well as the GERD dimension as assessed by Reflux Disease Questionnaire improved significantly. There was a significant improvement in the disease-specific quality of life as measured by the Gastrointestinal Quality of Life Index (p < 0.001) and by the Quality Of Life in Reflux and Dyspepsia (p < 0.001) questionnaires and the general health-related quality of life as assessed by SF-12 (p < 0.007). Conclusions: The present pilot study provides evidence that supplementation with natural mineral water rich in hydrogen carbonate may improve heartburn and dyspeptic symptoms, which finally resulted in an improvement of the subjectively perceived quality of life. Drinking mineral water rich in hydrogen carbonate may be an alternative remedy for the treatment of dyspeptic symptoms and heartburn. Trial Registration: Eudra CT No 2013-001256-36." @default.
• W2312969522 created "2016-06-24" @default.
• W2312969522 creator A5003516536 @default.
• W2312969522 creator A5033870101 @default.
• W2312969522 creator A5059785050 @default.
• W2312969522 creator A5071484124 @default.
• W2312969522 date "2016-01-01" @default.
• W2312969522 modified "2023-09-26" @default.
• W2312969522 title "Pilot Trial on the Efficacy and Safety of a Natural Mineral Water Rich in Hydrogen Carbonate on Functional Dyspepsia and Heartburn" @default.
• W2312969522 cites W1506603089 @default.
• W2312969522 cites W1971286694 @default.
• W2312969522 cites W1979919368 @default.
• W2312969522 cites W1981763819 @default.
• W2312969522 cites W1983820420 @default.
• W2312969522 cites W2006735857 @default.
• W2312969522 cites W2007797593 @default.
• W2312969522 cites W2019077208 @default.
• W2312969522 cites W2034282428 @default.
• W2312969522 cites W2044976832 @default.
• W2312969522 cites W2075383821 @default.
• W2312969522 cites W2078999658 @default.
• W2312969522 cites W2090749786 @default.
• W2312969522 cites W2091229314 @default.
• W2312969522 cites W2097477058 @default.
• W2312969522 cites W2098993249 @default.
• W2312969522 cites W2099999179 @default.
• W2312969522 cites W2119406097 @default.
• W2312969522 cites W2123279801 @default.
• W2312969522 cites W2127193591 @default.
• W2312969522 cites W2139003021 @default.
• W2312969522 cites W2156286274 @default.
• W2312969522 cites W2158366081 @default.
• W2312969522 cites W2159794114 @default.
• W2312969522 cites W2320271907 @default.
• W2312969522 cites W2395804907 @default.
• W2312969522 cites W2467330020 @default.
• W2312969522 cites W3187530962 @default.
• W2312969522 cites W61263224 @default.
• W2312969522 doi "https://doi.org/10.4236/ojgas.2016.63012" @default.
• W2312969522 hasPublicationYear "2016" @default.
• W2312969522 type Work @default.
• W2312969522 sameAs 2312969522 @default.
• W2312969522 citedByCount "1" @default.
• W2312969522 countsByYear W23129695222018 @default.
• W2312969522 crossrefType "journal-article" @default.
• W2312969522 hasAuthorship W2312969522A5003516536 @default.
• W2312969522 hasAuthorship W2312969522A5033870101 @default.
• W2312969522 hasAuthorship W2312969522A5059785050 @default.
• W2312969522 hasAuthorship W2312969522A5071484124 @default.
• W2312969522 hasBestOaLocation W23129695221 @default.
• W2312969522 hasConcept C126322002 @default.
• W2312969522 hasConcept C159110408 @default.
• W2312969522 hasConcept C1862650 @default.
• W2312969522 hasConcept C2776462128 @default.
• W2312969522 hasConcept C2779134260 @default.
• W2312969522 hasConcept C2779951463 @default.
• W2312969522 hasConcept C43270747 @default.
• W2312969522 hasConcept C71924100 @default.
• W2312969522 hasConcept C90924648 @default.
• W2312969522 hasConceptScore W2312969522C126322002 @default.
• W2312969522 hasConceptScore W2312969522C159110408 @default.
• W2312969522 hasConceptScore W2312969522C1862650 @default.
• W2312969522 hasConceptScore W2312969522C2776462128 @default.
• W2312969522 hasConceptScore W2312969522C2779134260 @default.
• W2312969522 hasConceptScore W2312969522C2779951463 @default.
• W2312969522 hasConceptScore W2312969522C43270747 @default.
• W2312969522 hasConceptScore W2312969522C71924100 @default.
• W2312969522 hasConceptScore W2312969522C90924648 @default.
• W2312969522 hasLocation W23129695221 @default.
• W2312969522 hasOpenAccess W2312969522 @default.
• W2312969522 hasPrimaryLocation W23129695221 @default.
• W2312969522 hasRelatedWork W1531087676 @default.
• W2312969522 hasRelatedWork W1992863400 @default.
• W2312969522 hasRelatedWork W2003068090 @default.
• W2312969522 hasRelatedWork W2027677946 @default.
• W2312969522 hasRelatedWork W2040076099 @default.
• W2312969522 hasRelatedWork W2046488785 @default.
• W2312969522 hasRelatedWork W2078999658 @default.
• W2312969522 hasRelatedWork W2095763692 @default.
• W2312969522 hasRelatedWork W2108986671 @default.
• W2312969522 hasRelatedWork W2110994484 @default.
• W2312969522 hasRelatedWork W2129806041 @default.
• W2312969522 hasRelatedWork W2162588414 @default.
• W2312969522 hasRelatedWork W2171148742 @default.
• W2312969522 hasRelatedWork W2403442013 @default.
• W2312969522 hasRelatedWork W2411836185 @default.
• W2312969522 hasRelatedWork W2549182595 @default.
• W2312969522 hasRelatedWork W2575214853 @default.
• W2312969522 hasRelatedWork W2891533338 @default.
• W2312969522 hasRelatedWork W3129173680 @default.
• W2312969522 hasRelatedWork W2060277219 @default.
• W2312969522 isParatext "false" @default.
• W2312969522 isRetracted "false" @default.
• W2312969522 magId "2312969522" @default.
• W2312969522 workType "article" @default.