Matches in SemOpenAlex for { <https://semopenalex.org/work/W2312983071> ?p ?o ?g. }
- W2312983071 abstract "Clinical peptidomics and metabolomics are two emerging “-omics” technologies with the potential not only to detect disease-specific markers, but also to give insight into the disease dependency of degradation processes and metabolic pathway alterations. However, despite their rapid evolution and major investments, a clinical breakthrough, such as the approval of a major cancer biomarker, is still out of sight. What are the reasons for this failure? In this review we focus on three important factors: sensitivity, specificity and the avoidance of bias. The way to clinical implementation of peptidomics and metabolomics is still hampered by many of the problems that had to be solved for genomics and proteomics in the past, as well as new ones that require the creation of new analytic, computational and interpretative techniques. The greatest challenge, however, will be the integration of information from different “-omics” subdisciplines into straightforward answers to clinical questions, for example, in the form of new, superior “meta-markers”." @default.
- W2312983071 created "2016-06-24" @default.
- W2312983071 creator A5007053035 @default.
- W2312983071 creator A5020167411 @default.
- W2312983071 creator A5046296570 @default.
- W2312983071 date "2013-06-06" @default.
- W2312983071 modified "2023-10-18" @default.
- W2312983071 title "Potentials and pitfalls of clinical peptidomics and metabolomics" @default.
- W2312983071 cites W139555845 @default.
- W2312983071 cites W1509926796 @default.
- W2312983071 cites W1537494447 @default.
- W2312983071 cites W1549733517 @default.
- W2312983071 cites W1765952798 @default.
- W2312983071 cites W1823974926 @default.
- W2312983071 cites W1965330922 @default.
- W2312983071 cites W1975953992 @default.
- W2312983071 cites W1979246104 @default.
- W2312983071 cites W1984243118 @default.
- W2312983071 cites W1991451169 @default.
- W2312983071 cites W2002242662 @default.
- W2312983071 cites W2004412219 @default.
- W2312983071 cites W2005820953 @default.
- W2312983071 cites W2006617902 @default.
- W2312983071 cites W2018509647 @default.
- W2312983071 cites W2019434020 @default.
- W2312983071 cites W2024089135 @default.
- W2312983071 cites W2026086741 @default.
- W2312983071 cites W2026756548 @default.
- W2312983071 cites W2028038006 @default.
- W2312983071 cites W2033300291 @default.
- W2312983071 cites W2034931345 @default.
- W2312983071 cites W2036368290 @default.
- W2312983071 cites W2040331591 @default.
- W2312983071 cites W2046499926 @default.
- W2312983071 cites W2047950884 @default.
- W2312983071 cites W2048202432 @default.
- W2312983071 cites W2048398689 @default.
- W2312983071 cites W2050060939 @default.
- W2312983071 cites W2052250694 @default.
- W2312983071 cites W2054473549 @default.
- W2312983071 cites W2058653140 @default.
- W2312983071 cites W2060733138 @default.
- W2312983071 cites W2065565905 @default.
- W2312983071 cites W2066440553 @default.
- W2312983071 cites W2068606970 @default.
- W2312983071 cites W2074932800 @default.
- W2312983071 cites W2075531085 @default.
- W2312983071 cites W2076501430 @default.
- W2312983071 cites W2076561160 @default.
- W2312983071 cites W2079733567 @default.
- W2312983071 cites W2084115201 @default.
- W2312983071 cites W2086689797 @default.
- W2312983071 cites W2094229819 @default.
- W2312983071 cites W2094550799 @default.
- W2312983071 cites W2101449835 @default.
- W2312983071 cites W2102357738 @default.
- W2312983071 cites W2104377150 @default.
- W2312983071 cites W2106995472 @default.
- W2312983071 cites W2108420460 @default.
- W2312983071 cites W2112316706 @default.
- W2312983071 cites W2112603564 @default.
- W2312983071 cites W2113153354 @default.
- W2312983071 cites W2114345835 @default.
- W2312983071 cites W2115258708 @default.
- W2312983071 cites W2116981159 @default.
- W2312983071 cites W2117394122 @default.
- W2312983071 cites W2118773575 @default.
- W2312983071 cites W2120277210 @default.
- W2312983071 cites W2120988323 @default.
- W2312983071 cites W2121270713 @default.
- W2312983071 cites W2121493056 @default.
- W2312983071 cites W2122860580 @default.
- W2312983071 cites W2128565159 @default.
- W2312983071 cites W2128789834 @default.
- W2312983071 cites W2133111499 @default.
- W2312983071 cites W2134389439 @default.
- W2312983071 cites W2135607659 @default.
- W2312983071 cites W2139621089 @default.
- W2312983071 cites W2142846876 @default.
- W2312983071 cites W2143283561 @default.
- W2312983071 cites W2147214095 @default.
- W2312983071 cites W2147464891 @default.
- W2312983071 cites W2151893606 @default.
- W2312983071 cites W2152330909 @default.
- W2312983071 cites W2152602715 @default.
- W2312983071 cites W2154066898 @default.
- W2312983071 cites W2155680682 @default.
- W2312983071 cites W2157492758 @default.
- W2312983071 cites W2158418996 @default.
- W2312983071 cites W2158912320 @default.
- W2312983071 cites W2161371306 @default.
- W2312983071 cites W2165015714 @default.
- W2312983071 cites W2165907193 @default.
- W2312983071 cites W2166196020 @default.
- W2312983071 doi "https://doi.org/10.4414/smw.2013.13801" @default.
- W2312983071 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23771768" @default.
- W2312983071 hasPublicationYear "2013" @default.
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