FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2312991010> ?p ?o ?g. }

• W2312991010 endingPage "S669" @default.
• W2312991010 startingPage "S664" @default.
• W2312991010 abstract "Moxalactam was compared with alternative antimicrobial agents for in vivo activity against Bacteroides fragilis. Mice were challenged with one of 15 strains and evaluated by quantitative bacteriologic analysis of abscess contents after five days of treatment. Optimal results were achieved with clindamycin, moxalactam, and cefoxitin. The mean decrease in bacteria with these three drugs was significantly greater than with chloramphenicol, cefotaxime, carbenicillin, cephalothin, ampicillin, and cefoperazone. The penetration of antimicrobial agents into subcutaneous abscesses was examined. The mean peak level in sterile abscesses of moxalactam was 27% of the mean peak serum level, a result indicating relatively good penetration compared with other beta-lactam antimicrobial agents. Stability of moxalactam to the beta-lactamase of B. fragilis was demonstrated in vivo by comparing levels of biologically active drug in sterile and infected abscesses and in vitro by comparing levels of antibiotic incubated in sterile exudate and exudate infected with B. fragilis. Moxalactam compares favorably with clindamycin and cefoxitin in activity against B. fragilis." @default.
• W2312991010 created "2016-06-24" @default.
• W2312991010 creator A5044626250 @default.
• W2312991010 creator A5061595032 @default.
• W2312991010 creator A5064734952 @default.
• W2312991010 creator A5082148123 @default.
• W2312991010 date "1982-11-01" @default.
• W2312991010 modified "2023-09-27" @default.
• W2312991010 title "Efficacy of Moxalactam in an Animal Model of Subcutaneous Abscesses: Penetration into Infected Sites and in Vivo Activity Against Bacteroides fragilis" @default.
• W2312991010 cites W1487133710 @default.
• W2312991010 cites W1965471644 @default.
• W2312991010 cites W1968571019 @default.
• W2312991010 cites W2000121475 @default.
• W2312991010 cites W2005372482 @default.
• W2312991010 cites W2021624945 @default.
• W2312991010 cites W2028433696 @default.
• W2312991010 cites W2031995165 @default.
• W2312991010 cites W2033981815 @default.
• W2312991010 cites W2038209477 @default.
• W2312991010 cites W2040132723 @default.
• W2312991010 cites W2042044657 @default.
• W2312991010 cites W2042229764 @default.
• W2312991010 cites W2054097711 @default.
• W2312991010 cites W2063227801 @default.
• W2312991010 cites W2073874951 @default.
• W2312991010 cites W2082913571 @default.
• W2312991010 cites W2096553293 @default.
• W2312991010 cites W2105305170 @default.
• W2312991010 cites W2106883529 @default.
• W2312991010 cites W2118287621 @default.
• W2312991010 cites W2142639690 @default.
• W2312991010 cites W2237870820 @default.
• W2312991010 cites W93649015 @default.
• W2312991010 cites W2104167763 @default.
• W2312991010 cites W2444292733 @default.
• W2312991010 doi "https://doi.org/10.1093/clinids/4.supplement_3.s664" @default.
• W2312991010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6218580" @default.
• W2312991010 hasPublicationYear "1982" @default.
• W2312991010 type Work @default.
• W2312991010 sameAs 2312991010 @default.
• W2312991010 citedByCount "3" @default.
• W2312991010 crossrefType "journal-article" @default.
• W2312991010 hasAuthorship W2312991010A5044626250 @default.
• W2312991010 hasAuthorship W2312991010A5061595032 @default.
• W2312991010 hasAuthorship W2312991010A5064734952 @default.
• W2312991010 hasAuthorship W2312991010A5082148123 @default.
• W2312991010 hasConcept C150903083 @default.
• W2312991010 hasConcept C207001950 @default.
• W2312991010 hasConcept C2776021129 @default.
• W2312991010 hasConcept C2776124114 @default.
• W2312991010 hasConcept C2776237055 @default.
• W2312991010 hasConcept C2776869330 @default.
• W2312991010 hasConcept C2777129096 @default.
• W2312991010 hasConcept C2777458120 @default.
• W2312991010 hasConcept C2778014902 @default.
• W2312991010 hasConcept C2778168646 @default.
• W2312991010 hasConcept C2778353156 @default.
• W2312991010 hasConcept C2778719061 @default.
• W2312991010 hasConcept C2779489039 @default.
• W2312991010 hasConcept C2779631663 @default.
• W2312991010 hasConcept C2779913634 @default.
• W2312991010 hasConcept C2780246119 @default.
• W2312991010 hasConcept C2780960513 @default.
• W2312991010 hasConcept C2909971615 @default.
• W2312991010 hasConcept C4937899 @default.
• W2312991010 hasConcept C501593827 @default.
• W2312991010 hasConcept C523546767 @default.
• W2312991010 hasConcept C54355233 @default.
• W2312991010 hasConcept C64778159 @default.
• W2312991010 hasConcept C71924100 @default.
• W2312991010 hasConcept C86803240 @default.
• W2312991010 hasConcept C89423630 @default.
• W2312991010 hasConcept C94665300 @default.
• W2312991010 hasConceptScore W2312991010C150903083 @default.
• W2312991010 hasConceptScore W2312991010C207001950 @default.
• W2312991010 hasConceptScore W2312991010C2776021129 @default.
• W2312991010 hasConceptScore W2312991010C2776124114 @default.
• W2312991010 hasConceptScore W2312991010C2776237055 @default.
• W2312991010 hasConceptScore W2312991010C2776869330 @default.
• W2312991010 hasConceptScore W2312991010C2777129096 @default.
• W2312991010 hasConceptScore W2312991010C2777458120 @default.
• W2312991010 hasConceptScore W2312991010C2778014902 @default.
• W2312991010 hasConceptScore W2312991010C2778168646 @default.
• W2312991010 hasConceptScore W2312991010C2778353156 @default.
• W2312991010 hasConceptScore W2312991010C2778719061 @default.
• W2312991010 hasConceptScore W2312991010C2779489039 @default.
• W2312991010 hasConceptScore W2312991010C2779631663 @default.
• W2312991010 hasConceptScore W2312991010C2779913634 @default.
• W2312991010 hasConceptScore W2312991010C2780246119 @default.
• W2312991010 hasConceptScore W2312991010C2780960513 @default.
• W2312991010 hasConceptScore W2312991010C2909971615 @default.
• W2312991010 hasConceptScore W2312991010C4937899 @default.
• W2312991010 hasConceptScore W2312991010C501593827 @default.
• W2312991010 hasConceptScore W2312991010C523546767 @default.
• W2312991010 hasConceptScore W2312991010C54355233 @default.
• W2312991010 hasConceptScore W2312991010C64778159 @default.
• W2312991010 hasConceptScore W2312991010C71924100 @default.
• W2312991010 hasConceptScore W2312991010C86803240 @default.

• next