Matches in SemOpenAlex for { <https://semopenalex.org/work/W2313007816> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2313007816 abstract "TNF receptor-associated periodic syndrome (TRAPS) is an autosomal dominant autoinflammatory disorder characterized by recurrent febrile attacks. TRAPS is associated with mutation in the gene encoding TNF Receptor I (TNFRI) and seven mutations have been reported in Japan. Molecular modeling experiments indicate that the mutant TNFRI accumulates intracellularly in the endoplasmic reticulum due to misfolding and activates MAP kinase (MAPK) through induction of mitochondrial reactive oxygen species production. MAPK activation is further enhanced by the stimulation through toll-like receptor, resulting in the enhanced proinflammatory cytokine production. Febrile attacks last 21 days on average and occur every one to several months. Myalgia, erythematous macular rash, abdominal pain, conjunctivitis, periorbital edema, chest pain and arthralgia are commonly seen during the attacks. Glucocorticoid is effective in decreasing the severity and duration of the febrile attacks. Soluble TNF receptor etanercept, IL-1 receptor antagonist Anakinra(TM) and IL-6 receptor antagonist tocilizumab are effective in some patients. Japanese study group of TRAPS conducted national survey to make new diagnostic criteria in 2010." @default.
- W2313007816 created "2016-06-24" @default.
- W2313007816 creator A5023749170 @default.
- W2313007816 creator A5030740263 @default.
- W2313007816 creator A5035492771 @default.
- W2313007816 date "2011-01-01" @default.
- W2313007816 modified "2023-10-16" @default.
- W2313007816 title "Progress in Classification and Treatment for TNF receptor-associated periodic syndrome" @default.
- W2313007816 cites W1969153089 @default.
- W2313007816 cites W1980698016 @default.
- W2313007816 cites W1986672711 @default.
- W2313007816 cites W1992328625 @default.
- W2313007816 cites W2007705302 @default.
- W2313007816 cites W2016246684 @default.
- W2313007816 cites W2018915861 @default.
- W2313007816 cites W2033023137 @default.
- W2313007816 cites W2064656238 @default.
- W2313007816 cites W2072208297 @default.
- W2313007816 cites W2076963123 @default.
- W2313007816 cites W2095013915 @default.
- W2313007816 cites W2097962902 @default.
- W2313007816 cites W2100998301 @default.
- W2313007816 cites W2105405561 @default.
- W2313007816 cites W2105545932 @default.
- W2313007816 cites W2119828139 @default.
- W2313007816 cites W2129069063 @default.
- W2313007816 cites W2140163728 @default.
- W2313007816 cites W2326861977 @default.
- W2313007816 cites W2336449142 @default.
- W2313007816 cites W79960063 @default.
- W2313007816 doi "https://doi.org/10.2177/jsci.34.361" @default.
- W2313007816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22041423" @default.
- W2313007816 hasPublicationYear "2011" @default.
- W2313007816 type Work @default.
- W2313007816 sameAs 2313007816 @default.
- W2313007816 citedByCount "6" @default.
- W2313007816 countsByYear W23130078162012 @default.
- W2313007816 countsByYear W23130078162014 @default.
- W2313007816 countsByYear W23130078162017 @default.
- W2313007816 crossrefType "journal-article" @default.
- W2313007816 hasAuthorship W2313007816A5023749170 @default.
- W2313007816 hasAuthorship W2313007816A5030740263 @default.
- W2313007816 hasAuthorship W2313007816A5035492771 @default.
- W2313007816 hasBestOaLocation W23130078161 @default.
- W2313007816 hasConcept C126322002 @default.
- W2313007816 hasConcept C164027704 @default.
- W2313007816 hasConcept C170493617 @default.
- W2313007816 hasConcept C203014093 @default.
- W2313007816 hasConcept C2776885963 @default.
- W2313007816 hasConcept C2776914184 @default.
- W2313007816 hasConcept C2778122271 @default.
- W2313007816 hasConcept C2779134260 @default.
- W2313007816 hasConcept C2781228260 @default.
- W2313007816 hasConcept C71924100 @default.
- W2313007816 hasConceptScore W2313007816C126322002 @default.
- W2313007816 hasConceptScore W2313007816C164027704 @default.
- W2313007816 hasConceptScore W2313007816C170493617 @default.
- W2313007816 hasConceptScore W2313007816C203014093 @default.
- W2313007816 hasConceptScore W2313007816C2776885963 @default.
- W2313007816 hasConceptScore W2313007816C2776914184 @default.
- W2313007816 hasConceptScore W2313007816C2778122271 @default.
- W2313007816 hasConceptScore W2313007816C2779134260 @default.
- W2313007816 hasConceptScore W2313007816C2781228260 @default.
- W2313007816 hasConceptScore W2313007816C71924100 @default.
- W2313007816 hasLocation W23130078161 @default.
- W2313007816 hasLocation W23130078162 @default.
- W2313007816 hasOpenAccess W2313007816 @default.
- W2313007816 hasPrimaryLocation W23130078161 @default.
- W2313007816 hasRelatedWork W1551727579 @default.
- W2313007816 hasRelatedWork W2013091470 @default.
- W2313007816 hasRelatedWork W2063619316 @default.
- W2313007816 hasRelatedWork W2116387684 @default.
- W2313007816 hasRelatedWork W2149275181 @default.
- W2313007816 hasRelatedWork W2337333432 @default.
- W2313007816 hasRelatedWork W2793218220 @default.
- W2313007816 hasRelatedWork W3002290290 @default.
- W2313007816 hasRelatedWork W3139920507 @default.
- W2313007816 hasRelatedWork W3157187218 @default.
- W2313007816 isParatext "false" @default.
- W2313007816 isRetracted "false" @default.
- W2313007816 magId "2313007816" @default.
- W2313007816 workType "article" @default.