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• W2313100065 abstract "Abstract Multiple infection of mass cultures of KB cells with type 2 adenovirus resulted in marked stimulation of incorporation of P32-orthophosphate into RNA mononucleotides and DNA. Studies at several time intervals revealed greatest incorporation of P32 into RNA at 9–18 hours, into DNA at both 9–18 and 18–27 hours after infection. The data are interpreted as indicating a virus-stimulated incorporation of medium P32 at 9–18 hours into the phosphate pool of the cell. At this time, the acid-soluble nucleotide and phospholipid fractions were also found to be more active in infected than in uninfected cells. The prolonged increased uptake of isotope into the DNA of the infected cell may reflect, in addition to a more highly labeled phosphate pool, a stimulated synthesis of a new DNA, perhaps virus precursor." @default.
• W2313100065 created "2016-06-24" @default.
• W2313100065 creator A5030738643 @default.
• W2313100065 date "1959-11-01" @default.
• W2313100065 modified "2023-09-27" @default.
• W2313100065 title "Biochemical studies on adenovirus multiplication" @default.
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• W2313100065 doi "https://doi.org/10.1016/0042-6822(59)90127-8" @default.
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