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- W2313139002 abstract "Background:Prediabetes substantially increases cardiovascular risk. We examined the effect of rosuvastatin on the quantity and quality of low-density lipoprotein cholesterol (LDL-C) in patients with dyslipidemia having impaired fasting glucose (IFG) compared to normoglycemic patients with dyslipidemia.Methods:This was a prospective observational study including patients with dyslipidemia and IFG (IFG group, n = 49) matched with normoglycemic patients with dyslipidemia (control group, n = 64). Study participants, following dietary intervention, were prescribed rosuvastatin 10 or 20 mg/d to achieve LDL-C goals. Baseline as well as 24 weeks posttreatment changes in the serum lipid profile were evaluated. Moreover, analysis of the LDL subfraction profile was conducted using a polyacrylamide tube gel electrophoresis method.Results:Similar effects were observed in lipid profile in both treatment groups. Patients with IFG experienced a greater decrease in the cholesterol concentration of small dense LDL particle..." @default.
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- W2313139002 date "2014-08-01" @default.
- W2313139002 modified "2023-09-25" @default.
- W2313139002 title "The effect of rosuvastatin on low-density lipoprotein subfractions in patients with impaired fasting glucose" @default.
- W2313139002 doi "https://doi.org/10.1016/j.atherosclerosis.2014.05.760" @default.
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