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• W2313140593 startingPage "2694" @default.
• W2313140593 abstract "An enriched fraction of an aqueous extract prepared from the aerial parts of Cyclopia genistoides Vent. yielded a new benzophenone di-C,O-glucoside, 3-C-β-d-glucopyranosyl-4-O-β-d-glucopyranosyliriflophenone (1), together with small quantities of a known benzophenone C-glucoside, 3-C-β-d-glucopyranosylmaclurin (2). The isolated compounds showed α-glucosidase inhibitory activity against an enzyme mixture extracted from rat intestinal acetone powder. Compound 2 exhibited significantly (p < 0.05) higher inhibitory activity (54%) than 1 (43%) at 200 μM. In vitro tests in several cell models showed that 1 and its 3-C-monoglucosylated derivative (3-C-β-d-glucopyranosyliriflophenone) were marginally effective (p ≥ 0.05) in increasing glucose uptake." @default.
• W2313140593 created "2016-06-24" @default.
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• W2313140593 date "2014-11-24" @default.
• W2313140593 modified "2023-10-16" @default.
• W2313140593 title "Benzophenone <i>C</i>- and <i>O</i>-Glucosides from <i>Cyclopia genistoides</i> (Honeybush) Inhibit Mammalian α-Glucosidase" @default.
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• W2313140593 doi "https://doi.org/10.1021/np5007247" @default.
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• W2313140593 hasPublicationYear "2014" @default.
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