FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2313169601> ?p ?o ?g. }

• W2313169601 endingPage "36" @default.
• W2313169601 startingPage "29" @default.
• W2313169601 abstract "The administration of dizocilpine, a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist acting at the associated ion channel, increased the grooming time induced in rats by the D1 dopamine receptor agonist SKF 38393 and the stereotyped behaviour elicited by the D1/D2 dopamine receptor agonist apomorphine, and reduced the locomotor response to the D2 dopamine receptor agonist quinpirole. This supports the view that glutamate deficiency plays an important role in the pathogenesis of schizophrenia by altering the balance between glutamatergic and dopaminergic systems. Blockade of serotonin receptors counteracted the effect of dizocilpine on dopaminergic responses. Both the non-selective 5HT1/5HT2 antagonist methysergide, and ketanserin, which more specifically blocks 5HT2 receptors, given at doses inhibiting serotonin-mediated behaviours but which did not affect spontaneous motility and dopaminergic behaviours, hampered the dizocilpine-induced potentiation of responses elicited by the stimulation of D1 or D1/D2 dopamine receptors and counteracted the dizocilpine-induced reduction of hyperactivity observed following quinpirole administration. The results suggest that the functional integrity of the serotonergic system is fundamental for the occurrence of dopaminergic changes resulting from non-competitive NMDA blockade." @default.
• W2313169601 created "2016-06-24" @default.
• W2313169601 creator A5059207270 @default.
• W2313169601 creator A5073724502 @default.
• W2313169601 creator A5076226950 @default.
• W2313169601 date "2000-02-01" @default.
• W2313169601 modified "2023-10-18" @default.
• W2313169601 title "Blockade of the serotonergic system counteracts the dizocilpine-induced changes in dopaminergic function" @default.
• W2313169601 cites W1540094813 @default.
• W2313169601 cites W1971547290 @default.
• W2313169601 cites W1984762359 @default.
• W2313169601 cites W1985094327 @default.
• W2313169601 cites W1988733687 @default.
• W2313169601 cites W1988836643 @default.
• W2313169601 cites W1989647306 @default.
• W2313169601 cites W1997402918 @default.
• W2313169601 cites W2002224654 @default.
• W2313169601 cites W2002596676 @default.
• W2313169601 cites W2004763052 @default.
• W2313169601 cites W2023946617 @default.
• W2313169601 cites W2044137171 @default.
• W2313169601 cites W2052852412 @default.
• W2313169601 cites W2052996136 @default.
• W2313169601 cites W2054111879 @default.
• W2313169601 cites W2054484015 @default.
• W2313169601 cites W2056664657 @default.
• W2313169601 cites W2064678154 @default.
• W2313169601 cites W2090909112 @default.
• W2313169601 cites W2092855120 @default.
• W2313169601 cites W2144461896 @default.
• W2313169601 cites W2314315659 @default.
• W2313169601 cites W2318210124 @default.
• W2313169601 cites W2413010420 @default.
• W2313169601 doi "https://doi.org/10.1097/00008877-200002000-00003" @default.
• W2313169601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10821206" @default.
• W2313169601 hasPublicationYear "2000" @default.
• W2313169601 type Work @default.
• W2313169601 sameAs 2313169601 @default.
• W2313169601 citedByCount "9" @default.
• W2313169601 countsByYear W23131696012012 @default.
• W2313169601 countsByYear W23131696012014 @default.
• W2313169601 countsByYear W23131696012017 @default.
• W2313169601 crossrefType "journal-article" @default.
• W2313169601 hasAuthorship W2313169601A5059207270 @default.
• W2313169601 hasAuthorship W2313169601A5073724502 @default.
• W2313169601 hasAuthorship W2313169601A5076226950 @default.
• W2313169601 hasConcept C120069818 @default.
• W2313169601 hasConcept C126322002 @default.
• W2313169601 hasConcept C137183658 @default.
• W2313169601 hasConcept C15744967 @default.
• W2313169601 hasConcept C169760540 @default.
• W2313169601 hasConcept C170493617 @default.
• W2313169601 hasConcept C185592680 @default.
• W2313169601 hasConcept C2775864247 @default.
• W2313169601 hasConcept C2777785214 @default.
• W2313169601 hasConcept C2777836312 @default.
• W2313169601 hasConcept C2778296116 @default.
• W2313169601 hasConcept C2778938600 @default.
• W2313169601 hasConcept C2781005078 @default.
• W2313169601 hasConcept C37000724 @default.
• W2313169601 hasConcept C44208683 @default.
• W2313169601 hasConcept C513476851 @default.
• W2313169601 hasConcept C53910766 @default.
• W2313169601 hasConcept C67018056 @default.
• W2313169601 hasConcept C71924100 @default.
• W2313169601 hasConcept C98274493 @default.
• W2313169601 hasConceptScore W2313169601C120069818 @default.
• W2313169601 hasConceptScore W2313169601C126322002 @default.
• W2313169601 hasConceptScore W2313169601C137183658 @default.
• W2313169601 hasConceptScore W2313169601C15744967 @default.
• W2313169601 hasConceptScore W2313169601C169760540 @default.
• W2313169601 hasConceptScore W2313169601C170493617 @default.
• W2313169601 hasConceptScore W2313169601C185592680 @default.
• W2313169601 hasConceptScore W2313169601C2775864247 @default.
• W2313169601 hasConceptScore W2313169601C2777785214 @default.
• W2313169601 hasConceptScore W2313169601C2777836312 @default.
• W2313169601 hasConceptScore W2313169601C2778296116 @default.
• W2313169601 hasConceptScore W2313169601C2778938600 @default.
• W2313169601 hasConceptScore W2313169601C2781005078 @default.
• W2313169601 hasConceptScore W2313169601C37000724 @default.
• W2313169601 hasConceptScore W2313169601C44208683 @default.
• W2313169601 hasConceptScore W2313169601C513476851 @default.
• W2313169601 hasConceptScore W2313169601C53910766 @default.
• W2313169601 hasConceptScore W2313169601C67018056 @default.
• W2313169601 hasConceptScore W2313169601C71924100 @default.
• W2313169601 hasConceptScore W2313169601C98274493 @default.
• W2313169601 hasIssue "1" @default.
• W2313169601 hasLocation W23131696011 @default.
• W2313169601 hasLocation W23131696012 @default.
• W2313169601 hasOpenAccess W2313169601 @default.
• W2313169601 hasPrimaryLocation W23131696011 @default.
• W2313169601 hasRelatedWork W1481546376 @default.
• W2313169601 hasRelatedWork W2036082219 @default.
• W2313169601 hasRelatedWork W2045726405 @default.
• W2313169601 hasRelatedWork W2059019392 @default.
• W2313169601 hasRelatedWork W2313169601 @default.
• W2313169601 hasRelatedWork W2405648434 @default.
• W2313169601 hasRelatedWork W2468466068 @default.

• next