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- W2313231778 abstract "Diffuse idiopathic skeletal hyperostosis (DISH) is a noninflammatory condition characterized by new bone growth affecting cancellous and cortical bone and particularly targeting the enthesis, that region where ligament, tendon, annulus fibrosis, and similar structures insert into cortical bone. Criteria for diagnosis are based on the radiological presence of entheseal ossification1,2, principally in the spine, where the new bone growth of DISH is ubiquitous.DISH is a common condition with prevalence rates that vary depending on the criteria applied and the population studied. Estimates range from 3.8% of men and 2.6% of women in a Finnish population-based study3, to 22.4% of men and 13.4% of women in an Israeli hospital-based study4. Its prevalence increases with age and hence with the aging population DISH will become more prevalent than before. There is a 2:1 male predominance in DISH, with severe radiological changes reported more commonly in males4. An association with obesity has been noted since the early description of the condition by Forestier and Rotes-Querol5, and over time, type 2 diabetes and the metabolic syndrome have also been identified as comorbid conditions6,7. The metabolic factors associated with DISH, despite decades of inquiry, still likely relate to insulin-associated growth factors and the effect of those factors on bone and entheseal growth plates8,9.As the population ages and as the proportion of metabolically vulnerable persons increases, so will the prevalence of DISH increase. Will this emerging epidemic of DISH increase the musculoskeletal health burden? In particular, will there be more pain and disability due to this disorder?Symptoms traditionally attributed to DISH include restriction in movement of spinal joints and entheseal-related …" @default.
- W2313231778 created "2016-06-24" @default.
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- W2313231778 date "2010-09-01" @default.
- W2313231778 modified "2023-10-01" @default.
- W2313231778 title "Is DISH Painful?" @default.
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- W2313231778 doi "https://doi.org/10.3899/jrheum.100519" @default.
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