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- W2313233415 abstract "A survey was conducted to determine the presence of hemagglutination- inhibiting (HI) and neutralizing (NT) antibodies against Newcastle disease virus in the serum of human beings that were engaged in vaccine production.A total of 156 human sera were collected from 64 persons exposed to virulent virus by contact (group A), 36 persons exposed to low virulent (B1 strain) virus (group B), and 56 persons notexposed to virus (group C), which served as controls.As a result, 12.9, 12.6, and 4.0 per cent of the tested were found to have the mean HI titer in groups A, B, and C, respectively. The mean NT titers were 0.73, 0.87, and 0.15 in groups A, B, and C, respectively It was assumed that an HI titer of 1: 16 or over and an NT titer of 1.0 or over might indicate a positive reaction. Then HI: 59.3% and NT: 45.3% of group A, HI: 38.8% and NT: 46.9% of group B, and HI: 0% and NT: 5.3% of group C were found to give a positive test. There was no difference in antibody titer of human serum between exposure to the virulent virus and that to the low virulent virus. The more frequently human beings were exposed to the virus, the higher antibody titer they obtained. those who were constantly exposed to the virus showed no clinical signs while working. These results suggest that exposure to Newcastle disease virus may lead to latent infection in human beings." @default.
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- W2313233415 date "1969-01-01" @default.
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- W2313233415 title "Prevalence of Antibodies Against Newcastle Disease Virus in Human Serum" @default.
- W2313233415 doi "https://doi.org/10.12935/jvma1951.22.418" @default.
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