Matches in SemOpenAlex for { <https://semopenalex.org/work/W2313295756> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2313295756 endingPage "1178" @default.
- W2313295756 startingPage "1169" @default.
- W2313295756 abstract "Purpose The aim of this study was to develop a simple noninvasive method for measuring blood flow using [15O]H2O PET/CT for the head and neck area applicable in daily clinical practice. Patients and methods Fifteen dynamic [15O]H2O PET emission scans with simultaneous online radioactivity measurements of radial arterial blood [Blood-input functions (IFs)] were performed. Two noninvasively obtained population-based input functions were calculated by averaging all Blood-IF curves corrected for patients’ body mass and injected dose [standardized uptake value (SUV)-IF] and for body surface area (BSA-IF) and injected dose. Parametric perfusion images were calculated for each set of IFs using a linearized two-compartment model, and values for several tissues were compared using Blood-IF as the gold standard. Results On comparing all tissues, the correlation between blood flow obtained with the invasive Blood-IF and both SUV-IF and BSA-IF was significant (R2=0.785 with P<0.001 and R2=0.813 with P<0.001, respectively). In individual tissues, the performance of the two noninvasive methods was most reliable in resting muscle and slightly less reliable in tumour and cerebellar regions. In these two tissues, only BSA-IF showed a significant correlation with Blood-IF (R2=0.307 with P=0.032 in tumours and R2=0.398 with P<0.007 in the cerebellum). Conclusion The BSA-based noninvasive method enables clinically relevant delineation between areas of low and high blood flow in tumours. The blood flow of low-perfusion tissues can be reliably quantified using either of the evaluated noninvasive methods." @default.
- W2313295756 created "2016-06-24" @default.
- W2313295756 creator A5013510442 @default.
- W2313295756 creator A5047777821 @default.
- W2313295756 creator A5059466134 @default.
- W2313295756 creator A5079100857 @default.
- W2313295756 creator A5087536800 @default.
- W2313295756 date "2012-11-01" @default.
- W2313295756 modified "2023-10-02" @default.
- W2313295756 title "Noninvasive parametric blood flow imaging of head and neck tumours using [15O]H2O and PET/CT" @default.
- W2313295756 cites W1600041372 @default.
- W2313295756 cites W1969451158 @default.
- W2313295756 cites W1997429901 @default.
- W2313295756 cites W2008001364 @default.
- W2313295756 cites W2008413151 @default.
- W2313295756 cites W2015711048 @default.
- W2313295756 cites W2032401196 @default.
- W2313295756 cites W2036232598 @default.
- W2313295756 cites W2100148774 @default.
- W2313295756 cites W2127200853 @default.
- W2313295756 cites W2127367027 @default.
- W2313295756 cites W2142148333 @default.
- W2313295756 cites W2143967388 @default.
- W2313295756 cites W2152272294 @default.
- W2313295756 cites W2293035635 @default.
- W2313295756 cites W2320852574 @default.
- W2313295756 doi "https://doi.org/10.1097/mnm.0b013e3283579e6e" @default.
- W2313295756 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22863762" @default.
- W2313295756 hasPublicationYear "2012" @default.
- W2313295756 type Work @default.
- W2313295756 sameAs 2313295756 @default.
- W2313295756 citedByCount "8" @default.
- W2313295756 countsByYear W23132957562013 @default.
- W2313295756 countsByYear W23132957562014 @default.
- W2313295756 countsByYear W23132957562015 @default.
- W2313295756 countsByYear W23132957562018 @default.
- W2313295756 countsByYear W23132957562022 @default.
- W2313295756 countsByYear W23132957562023 @default.
- W2313295756 crossrefType "journal-article" @default.
- W2313295756 hasAuthorship W2313295756A5013510442 @default.
- W2313295756 hasAuthorship W2313295756A5047777821 @default.
- W2313295756 hasAuthorship W2313295756A5059466134 @default.
- W2313295756 hasAuthorship W2313295756A5079100857 @default.
- W2313295756 hasAuthorship W2313295756A5087536800 @default.
- W2313295756 hasConcept C126322002 @default.
- W2313295756 hasConcept C126838900 @default.
- W2313295756 hasConcept C135691158 @default.
- W2313295756 hasConcept C141071460 @default.
- W2313295756 hasConcept C146957229 @default.
- W2313295756 hasConcept C158846371 @default.
- W2313295756 hasConcept C2777501473 @default.
- W2313295756 hasConcept C2908647359 @default.
- W2313295756 hasConcept C2989005 @default.
- W2313295756 hasConcept C3018411727 @default.
- W2313295756 hasConcept C71924100 @default.
- W2313295756 hasConcept C99454951 @default.
- W2313295756 hasConceptScore W2313295756C126322002 @default.
- W2313295756 hasConceptScore W2313295756C126838900 @default.
- W2313295756 hasConceptScore W2313295756C135691158 @default.
- W2313295756 hasConceptScore W2313295756C141071460 @default.
- W2313295756 hasConceptScore W2313295756C146957229 @default.
- W2313295756 hasConceptScore W2313295756C158846371 @default.
- W2313295756 hasConceptScore W2313295756C2777501473 @default.
- W2313295756 hasConceptScore W2313295756C2908647359 @default.
- W2313295756 hasConceptScore W2313295756C2989005 @default.
- W2313295756 hasConceptScore W2313295756C3018411727 @default.
- W2313295756 hasConceptScore W2313295756C71924100 @default.
- W2313295756 hasConceptScore W2313295756C99454951 @default.
- W2313295756 hasIssue "11" @default.
- W2313295756 hasLocation W23132957561 @default.
- W2313295756 hasLocation W23132957562 @default.
- W2313295756 hasOpenAccess W2313295756 @default.
- W2313295756 hasPrimaryLocation W23132957561 @default.
- W2313295756 hasRelatedWork W2102240528 @default.
- W2313295756 hasRelatedWork W2154749109 @default.
- W2313295756 hasRelatedWork W2313295756 @default.
- W2313295756 hasRelatedWork W2356249032 @default.
- W2313295756 hasRelatedWork W2362717301 @default.
- W2313295756 hasRelatedWork W2370053213 @default.
- W2313295756 hasRelatedWork W2382350448 @default.
- W2313295756 hasRelatedWork W2387390781 @default.
- W2313295756 hasRelatedWork W2444408921 @default.
- W2313295756 hasRelatedWork W3032311490 @default.
- W2313295756 hasVolume "33" @default.
- W2313295756 isParatext "false" @default.
- W2313295756 isRetracted "false" @default.
- W2313295756 magId "2313295756" @default.
- W2313295756 workType "article" @default.