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- W2313307762 abstract "Rouffiac V, P´eronneau P, Hadengue A, et al. A new ultrasound principle for characterizing erythrocyte aggregation. In vitro reproducibility and validation. Invest Radiol 2002;37:413–420. rationale and objectives. There is no method currently available to quantify erythrocyte aggregation in vivo. In this work, using a Couette system, we defined new ultrasound indexes potentially applicable for non-invasive investigations. methods. Two ultrasound protocols were developed: (1) a protocol in which decreasing shear rates ranging from 200 to 1 s−1 were applied to solutions; and (2) a protocol in which a 200 s−1 shear rate was initially applied followed by stoppage of flow (a kinetics protocol). New ultrasound indexes were defined as: the power PUS at the nominal frequency of each transducer, Rayleigh’s slope (tangent of the curve PUS = f(log(F)) through the 3.5 to 15 MHz frequency bandwidth) and kinetic indexes characterizing the aggregation/aggregability of the suspension. results. Using washed erythrocytes resuspended in saline, it was shown that the ultrasound intensity is dependent at 3.54 ± 5.9% (NS) to the power of the frequency (theoretical value = 4). Using 10 total blood samples extracted from a single pig, good reproducibility for all indexes (5%) was demonstrated. conclusions. A suitable and reproducible methodology was developed and validated for studying erythrocyte aggregation in calibrated in vitro conditions." @default.
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- W2313307762 date "2002-08-01" @default.
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- W2313307762 title "A New Ultrasound Principle for Characterizing Erythrocyte Aggregation" @default.
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- W2313307762 doi "https://doi.org/10.1097/00004424-200208000-00001" @default.
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