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- W2313384570 abstract "In August 1988, CDC /HCFA proposed new regulations to replace the minimum specifications that all US proficiency testing (PT) programs must meet or exceed to certify laboratory performance under Medicare or CLIA. Certification is to be based on outcome measurements, ie, PT performance. Scientists have long questioned the basic premise ofPT, namely, that evaluation samples are tested in precisely the same manner as routine patient samples. The proposed regulations specifically require this practice. The present study evaluates the effect of the widely acknowledged practice of replicate analyses of PT specimens and the effect on outcome measurements. A laboratory averaging 5 replicates reduces its apparent internal coefficient of variation by more than 50% and hence improves its FT performance. Moreover, a laboratory participating in a PT program where replicate analyses of PT specimens are common will suffer from beingheldto a higher standard of performance than its peers when grading criteria are based on interlaboratory SDs." @default.
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- W2313384570 date "1989-06-01" @default.
- W2313384570 modified "2023-09-24" @default.
- W2313384570 title "Performance of External Quality Control Systems" @default.
- W2313384570 cites W1858753925 @default.
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- W2313384570 doi "https://doi.org/10.1093/labmed/20.6.428" @default.
- W2313384570 hasPublicationYear "1989" @default.
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