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- W2313407838 abstract "Ultrastructural changes of the glomeruli were examined in the kidneys without gross lesions from 32 slaughtered pigs aged about six months. Of these, 24 pigs showed diffuse global mesangial enlargement with definite IgG and C3 deposition, and other eight had slight or no change in the glomeruli with little or no IgG or C3 deposition. The major ultrastructural abnormality was the electron-dense deposits in subendothelial, subepithelial and most frequently mesangial areas. Of the deposits in the mesangium, paramesangial ones were most characteristic. The degree of the deposition of electron-dense deposits generally coincided with that in light and immunofluorescence microscopy. In 20 of the 32 pigs, the clusters of spherical microparticles (SMP) were present in the mesangial, intramembranous, subendothelial and most frequently subepithelial areas. The incidence of SMP did not always coincide with the intensity in light microscopy, the immunofluorescent antibody test or the deposition of dense deposits. No conspicuous lesions of the glomerular basement membrane were observed except the electron-dense deposits and SMP." @default.
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- W2313407838 date "1988-01-01" @default.
- W2313407838 modified "2023-09-23" @default.
- W2313407838 title "Ultrastructure of glomerulopathy in swine." @default.
- W2313407838 doi "https://doi.org/10.1292/jvms1939.50.1" @default.
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