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- W2313442613 endingPage "50" @default.
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- W2313442613 abstract "T-cell mediated adaptive immunity against viruses relies on recognition of virus-derived peptides by CD4(+) and CD8(+) T cells. Detection of pathogen-derived peptide-MHC-I complexes triggers CD8(+) T cells to eliminate the infected cells. Viruses have evolved several mechanisms to avoid recognition, many of which target the MHC-I antigen-processing pathway. While many immune evasion strategies have been described in the context of herpesvirus infections, it is becoming clear that this 'disguise' ability is more widespread. Here, we address recent findings in viral evasion of the MHC-I antigen presentation pathway and the impact on CD8(+) T cell responses." @default.
- W2313442613 created "2016-06-24" @default.
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- W2313442613 date "2016-06-01" @default.
- W2313442613 modified "2023-09-26" @default.
- W2313442613 title "Recent advances in viral evasion of the MHC Class I processing pathway" @default.
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- W2313442613 doi "https://doi.org/10.1016/j.coi.2016.02.007" @default.
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