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- W2313459827 abstract "MacNeal and his coworkers1, 2 have successfully transferred to rabbits the human strains of Streptococcus viridans obtained from active cases of subacute bacterial endocarditis. The vegetative lesions developed in rabbits on the cardiac valves, which however were not known to be previously injured or diseased. Other localizations of the infection were often present. The diagnosis of endocarditis before death was attempted on the basis of successively positive blood cultures, development of anorexia and marked loss of weight. These criteria were often inadequate, as proved by autopsy.The difficulty in antemortem diagnosis of active experimental endocarditis has greatly hampered the therapeutic approach to this problem, which is admittedly an important one. In view of the large valvular lesions developed, often producing a severe stenosis, it was logical to assume the development of murmurs and modification of the heart tones. Therefore each animal was examined at frequent intervals, in unbiased procedures,..." @default.
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- W2313459827 date "1941-04-01" @default.
- W2313459827 modified "2023-09-26" @default.
- W2313459827 title "Role of Heart Sounds in Diagnosis of Experimental Endocarditis Lenta in Rabbits Before Death." @default.
- W2313459827 doi "https://doi.org/10.3181/00379727-46-12056p" @default.
- W2313459827 hasPublicationYear "1941" @default.
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