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• W2313537066 abstract "The present work describes an improved process for preparation of silica aerogel microparticles (SAMs) for drug delivery from rice husk ash (RHA), an inexpensive source rich in biocompatible silica. The wet gel microparticles were produced by a sol–gel method using water-in-oil emulsion, where a mineral oil replaced vegetable oil for easy separation using less energy. Taguchi design of experiments was used to optimize the parameters controlling the sol–gel method. The wet gel particles were dried with supercritical carbon dioxide (scCO2) to obtain SAMs. They were characterized by their properties such as BET surface area, pore volume, pore diameter and morphology. The efficacy of the improved process was validated by loading a water insoluble drug, ibuprofen, and a food preservative, eugenol, in SAMs from scCO2 medium. The release kinetics of ibuprofen and eugenol from the loaded SAMs was studied. High loading and fast release kinetics confirmed that SAMs produced by the process are suitable for drug delivery." @default.
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• W2313537066 date "2015-01-14" @default.
• W2313537066 modified "2023-10-04" @default.
• W2313537066 title "Silica Aerogel Microparticles from Rice Husk Ash for Drug Delivery" @default.
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• W2313537066 doi "https://doi.org/10.1021/ie503867p" @default.
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