FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2313549116> ?p ?o ?g. }

• W2313549116 abstract "Abstract The results of highthroughput practical single channel experiments should be formulated and validated by signal analysis approaches to increase the recognition precision of translocating molecules. For this purpose, the activities of the single nano-pore forming protein, OmpF, in the presence of nucleotides were recorded in real time by the voltage clamp technique and used as a means for nucleotide recognition. The results were analyzed based on the permutation entropy of current Time Series (TS), fractality, autocorrelation, structure function, spectral density, and peak fraction to recognize each nucleotide, based on its signature effect on the conductance, gating frequency and voltage sensitivity of channel at different concentrations and membrane potentials. The amplitude and frequency of ion current fluctuation increased in the presence of Adenine more than Cytosine and Thymine in milli-molar ( 0.5 mM ) concentrations. The variance of the current TS at various applied voltages showed a non-monotonic trend whose initial increasing slope in the presence of Thymine changed to a decreasing one in the second phase and was different from that of Adenine and Cytosine; e.g., by increasing the voltage from 40 to 140 mV in the 0.5 mM concentration of Adenine or Cytosine, the variance decreased by one third while for the case of Thymine it was doubled. Moreover, according to the structure function of TS, the fractality of current TS differed as a function of varying membrane potentials (pd) and nucleotide concentrations. Accordingly, the calculated permutation entropy of the TS, validated the biophysical approach defined for the recognition of different nucleotides at various concentrations, pd’s and polarities. Thus, the promising outcomes of the combined experimental and theoretical methodologies presented here can be implemented as a complementary means in pore-based nucleotide recognition approaches." @default.
• W2313549116 created "2016-06-24" @default.
• W2313549116 creator A5016271531 @default.
• W2313549116 creator A5020815488 @default.
• W2313549116 creator A5036206356 @default.
• W2313549116 creator A5063632511 @default.
• W2313549116 date "2016-09-01" @default.
• W2313549116 modified "2023-09-29" @default.
• W2313549116 title "OmpF, a nucleotide-sensing nanoprobe, computational evaluation of single channel activities" @default.
• W2313549116 cites W147998453 @default.
• W2313549116 cites W1486206726 @default.
• W2313549116 cites W1522687115 @default.
• W2313549116 cites W1544578519 @default.
• W2313549116 cites W1558220791 @default.
• W2313549116 cites W1963982927 @default.
• W2313549116 cites W1964988229 @default.
• W2313549116 cites W1966861188 @default.
• W2313549116 cites W1972074942 @default.
• W2313549116 cites W1974935655 @default.
• W2313549116 cites W1975331190 @default.
• W2313549116 cites W1976481076 @default.
• W2313549116 cites W1977079982 @default.
• W2313549116 cites W1978663383 @default.
• W2313549116 cites W1983360160 @default.
• W2313549116 cites W1983423377 @default.
• W2313549116 cites W1986418251 @default.
• W2313549116 cites W1988901585 @default.
• W2313549116 cites W1989734554 @default.
• W2313549116 cites W1992326333 @default.
• W2313549116 cites W1992539915 @default.
• W2313549116 cites W1993645861 @default.
• W2313549116 cites W1996764065 @default.
• W2313549116 cites W1997398658 @default.
• W2313549116 cites W1997641437 @default.
• W2313549116 cites W1999646223 @default.
• W2313549116 cites W2005727931 @default.
• W2313549116 cites W2012093444 @default.
• W2313549116 cites W2014683958 @default.
• W2313549116 cites W2015467993 @default.
• W2313549116 cites W2017091714 @default.
• W2313549116 cites W2023278686 @default.
• W2313549116 cites W2024386772 @default.
• W2313549116 cites W2029648392 @default.
• W2313549116 cites W2029953061 @default.
• W2313549116 cites W2031263866 @default.
• W2313549116 cites W2031409820 @default.
• W2313549116 cites W2036105970 @default.
• W2313549116 cites W2051524724 @default.
• W2313549116 cites W2053457342 @default.
• W2313549116 cites W2054988643 @default.
• W2313549116 cites W2056194813 @default.
• W2313549116 cites W2059578847 @default.
• W2313549116 cites W2062306783 @default.
• W2313549116 cites W2072982200 @default.
• W2313549116 cites W2092305751 @default.
• W2313549116 cites W2093239605 @default.
• W2313549116 cites W2094162382 @default.
• W2313549116 cites W2097933838 @default.
• W2313549116 cites W2114539124 @default.
• W2313549116 cites W2118457378 @default.
• W2313549116 cites W2118609874 @default.
• W2313549116 cites W2119249597 @default.
• W2313549116 cites W2120061656 @default.
• W2313549116 cites W2122797035 @default.
• W2313549116 cites W2125733064 @default.
• W2313549116 cites W2127407003 @default.
• W2313549116 cites W2132569635 @default.
• W2313549116 cites W2134836213 @default.
• W2313549116 cites W2139859673 @default.
• W2313549116 cites W2148332776 @default.
• W2313549116 cites W2167441750 @default.
• W2313549116 cites W2170569474 @default.
• W2313549116 cites W2479877058 @default.
• W2313549116 cites W384725478 @default.
• W2313549116 cites W564665047 @default.
• W2313549116 doi "https://doi.org/10.1016/j.physa.2016.03.031" @default.
• W2313549116 hasPublicationYear "2016" @default.
• W2313549116 type Work @default.
• W2313549116 sameAs 2313549116 @default.
• W2313549116 citedByCount "2" @default.
• W2313549116 countsByYear W23135491162019 @default.
• W2313549116 crossrefType "journal-article" @default.
• W2313549116 hasAuthorship W2313549116A5016271531 @default.
• W2313549116 hasAuthorship W2313549116A5020815488 @default.
• W2313549116 hasAuthorship W2313549116A5036206356 @default.
• W2313549116 hasAuthorship W2313549116A5063632511 @default.
• W2313549116 hasConcept C104317684 @default.
• W2313549116 hasConcept C113196181 @default.
• W2313549116 hasConcept C121332964 @default.
• W2313549116 hasConcept C121932024 @default.
• W2313549116 hasConcept C12554922 @default.
• W2313549116 hasConcept C181911157 @default.
• W2313549116 hasConcept C185592680 @default.
• W2313549116 hasConcept C26873012 @default.
• W2313549116 hasConcept C2776023528 @default.
• W2313549116 hasConcept C2776858809 @default.
• W2313549116 hasConcept C2994266630 @default.
• W2313549116 hasConcept C43617362 @default.
• W2313549116 hasConcept C512185932 @default.
• W2313549116 hasConcept C552990157 @default.

• next