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- W2313587685 abstract "The lesion in 18 cases of oral lichen planus and the surrounding site about 10mm from the focus, which appeared normal as seen with the eye, were examined by the direct immunofluorescent and histopathological methods. These results were compared with 13 cases of leukoplakia examined in the same way. The results were as follows.1. For hyperkeratosis, degeneration of the basal layer of epithelium and a dense band of lymphocytes adjacent to the epithelium, which are thought to be very important in histopathologically diagnosing oral lichen planus, the incidence was 100%, 89% and 100%, respectively, whereas the incidence of these findings at the surrounding site of the lesion was 56%, 44% and 78%. Eleven cases (61%) including more than 2 of the above 3 findings could be seen among the 18 cases. In the leukoplakia, the incidence of hyperkeratosis, acanthosis and inflammatory cell infiltration, which are thought to be very important for the histopathological diagnosis, was lower in the surrounding site of the lesion than in the focus.2. In lichen planus the deposition of fibrinogen was often observed both in the focus and in the surrounding site of the lesion, and there was little difference in the localization of these sites in the complement. However, a clear difference between the focus and the surrounding site of the lesion was detected in the case of leukoplakia.3. These results suggest that some histopathological changes have already occurred in the surrounding site of the lesion in lichen planus, and therefore medication may be preferable to surgical therapy. On the other hand, surgical therapy is considered to be a sure method in leukoplakia." @default.
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- W2313587685 date "1991-01-01" @default.
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- W2313587685 title "Histopathological study between lesion and the surrounding site of oral lichen planus and leukoplakia." @default.
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- W2313587685 doi "https://doi.org/10.5794/jjoms.37.1122" @default.
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