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- W2313783524 abstract "A new aromatic ester, pilobolusate (<b>1</b>), four new depsidones, pilobolusones A–D (<b>2</b>–<b>5</b>), five known depsidones, (<b>6</b>–<b>10</b>), and ergosterol were isolated from the fungus <i>Pilobolus heterosporus</i>. Their structures were established on the basis of spectroscopic data. Compounds <b>2</b> and <b>4</b>–<b>9</b> showed cytotoxicity against three cancer cell lines (KB, MCF-7, and NCI-H187) with IC<sub>50</sub> values in the range of 9.94–97.42 µM. In addition, compounds <b>2, 5, 9</b>, and <b>10</b> exhibited antimalarial activity against <i>Plasmodium falciparum</i> with IC<sub>50</sub> values ranging from 3.67–23.56 µM." @default.
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- W2313783524 date "2014-09-23" @default.
- W2313783524 modified "2023-10-16" @default.
- W2313783524 title "Bioactive Depsidones from the Fungus Pilobolus heterosporus" @default.
- W2313783524 doi "https://doi.org/10.1055/s-0034-1383082" @default.
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