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- W2313794893 abstract "Cisplatin and its analogues display common drawbacks such as unfavorable toxicological profile, short blood circulation time and non-specific bio-distribution. Besides that, in biological fluids cisplatin is inactivated by nitrogenand sulphur-containing biomolecules. Drug conjugation to a water soluble polymer is a feasible approach to enhance therapeutic efficiency. Examples of carboxylate-containing polymer carriers of cisplatin and the effect of macromolecular architecture on the behavior of conjugates are discussed." @default.
- W2313794893 created "2016-06-24" @default.
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- W2313794893 date "2014-01-01" @default.
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- W2313794893 title "Macromolecular Design of Platinum Drug Conjugates" @default.
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- W2313794893 doi "https://doi.org/10.4172/2167-065x.s2-006" @default.
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