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- W2313876978 abstract "BackgroundAlthough the colonic lumen is known to be largely devoid of oxygen, the mechanism by which this anaerobic environment is maintained remains unclear due to the inability of available technology to quantify oxygen in the intestinal tract. Indeed, most microbes in the gut are obligate anaerobes. Accurate quantification of oxygen in the gut is essential to elucidate the host’s relationship with its densely populated intestinal microbial community and may be relevant to various disease states in humans, including inflammatory bowel disease (IBD). For instance, multiple studies have demonstrated significant alterations in the gut microbiota in IBD, notably phylum level increases in Proteobacteria and Actinobacteria, which contain predominantly oxygen tolerant organisms, and a decrease in oxygen-sensitive Firmicutes." @default.
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- W2313876978 date "2012-12-01" @default.
- W2313876978 modified "2023-10-18" @default.
- W2313876978 title "An Oxygen Equilibrium at the Host-Microbial Interface Determined by Phosphorescent Nanoprobe Technology" @default.
- W2313876978 doi "https://doi.org/10.1097/00054725-201212001-00290" @default.
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