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- W2313953478 abstract "The molecular chaperone Hsp90 is what appears to be the Achilles' heel of fungal pathogens—a target that, once inhibited, helps to avoid or overcome resistance to other antifungal drugs, according to Leah Cowen of the University of Toronto in Toronto, Ontario, Canada. However, because similar chaperone proteins are found in mammals, this approach will need some fine-tuning to avoid toxicities, she points out. Cowen spoke during the symposium, “New Approaches in the Treatment of Fungal Infections,” convened as part of the 2012 ICAAC, held in San Francisco last September." @default.
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- W2313953478 date "2012-12-01" @default.
- W2313953478 modified "2023-09-26" @default.
- W2313953478 title "Combating Drug-Resistant Fungi" @default.
- W2313953478 doi "https://doi.org/10.1128/microbe.7.546.1" @default.
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