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- W2313961856 abstract "Propos. – L'arthrose est aujourd'hui l'une des pathologies les plus fréquentes et constitue ainsi l'une des principales priorités de santé publique au prorata du vieillissement de la population. Cette revue générale de la prise en charge thérapeutique médicamenteuse de l'arthrose est effectuée à la lumière de récentes études contrôlées. Actualités et points forts. – Quelques essais contrôlés semblent démontrer une supériorité antalgique des anti-inflammatoires non stéroïdiens sur le paracétamol. Quelques études documentent l'effet structural potentiel des médicaments dits antiarthrosiques symptomatiques d'action lente. Parmi les traitements locaux, la place de la viscosupplémentation apparaît de mieux en mieux documentée. À l'inverse, des travaux contrôlés récents ne confirment pas l'efficacité du lavage articulaire ou du débridement arthroscopique. Perspectives et projets. – À la lumière de plusieurs récentes recommandations internationales, il apparaît nécessaire d'optimiser à l'échelon individuel la meilleure combinaison de modalités thérapeutiques pharmacologiques et non médicamenteuses. Reste à déterminer plus précisément la place et les modalités d'utilisation des traitements dits symptomatiques d'action lente. Comment. – Osteoarthritis represents one of the most frequent pathologies today and so constitutes one of the main priorities of health service in proportion to the ageing of the population. This general review of the pharmacological therapies of osteoarthritis is conducted in the light of recent controlled studies. News and key points. – Some controlled studies seem to demonstrate an analgesic superiority of the non steroidal anti-inflammatory drugs versus acetaminophen. Some studies suggest the potential structural effect of so called slow-acting symptom modifying drugs. Among the local treatments, the interest of the viscosupplementation seems well established. On the contrary, recent controlled studies do not confirm the efficiency of the articular lavage or of the arthroscopic debridment. Perspectives and projects. – In the light of several recent international guidelines, it seems necessary to optimise in the individual patient the best possible combination of pharmacological and not medicinal therapeutic modalities. The place and the modalities of use of the slow-acting symptom modifying drugs remain to be determined more precisely." @default.
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- W2313961856 date "2003-03-01" @default.
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- W2313961856 title "La prise en charge thérapeutique de l'arthrose en ce début de 3e millénaire." @default.
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