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- W2314117615 abstract "An efficient asymmetric synthesis of atorvastatin calcium has been achieved from commercially available diethyl 3-hydroxyglutarate through a novel approach that involves an organocatalytic enantioselective cyclic anhydride desymmetrization to establish C(3) stereogenicity and cyanide-free assembly of C7 amino type side chain via C5+C2 strategy as the key transformations." @default.
- W2314117615 created "2016-06-24" @default.
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- W2314117615 date "2014-03-06" @default.
- W2314117615 modified "2023-09-27" @default.
- W2314117615 title "Asymmetric Synthesis of the HMG-CoA Reductase Inhibitor Atorvastatin Calcium: An Organocatalytic Anhydride Desymmetrization and Cyanide-Free Side Chain Elongation Approach" @default.
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- W2314117615 doi "https://doi.org/10.1021/jo402829b" @default.
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