Matches in SemOpenAlex for { <https://semopenalex.org/work/W2314270325> ?p ?o ?g. }
- W2314270325 endingPage "3011" @default.
- W2314270325 startingPage "3003" @default.
- W2314270325 abstract "We herein report a highly efficient method for the arylation at the C-5 position of N-aryl 1,2,3-triazoles via a direct palladium catalyzed arylation reaction. The optimal reaction conditions required a combination of Pd(OAc)2 and tris(o-tolyl)phosphine as catalyst, and Cs2CO3 as the base under inert atmosphere. A variety of C-5 substituted N-aryl 1,2,3-triazoles were prepared using these conditions with yields in the 70-88% range. Regioselective C-5 arylations were also performed on 1,4-disubstituted 1,2,3-triazoles. The regioselectivity in triazole substitution at the C-5 position was confirmed by single crystal XRD. In addition, computational investigations of key steps of the catalytic cycle using the density functional theory have provided a rationalization to the selective C-5 arylation of N-aryl 1,2,3-triazoles." @default.
- W2314270325 created "2016-06-24" @default.
- W2314270325 creator A5049314202 @default.
- W2314270325 creator A5050261459 @default.
- W2314270325 creator A5053675041 @default.
- W2314270325 date "2015-03-04" @default.
- W2314270325 modified "2023-10-18" @default.
- W2314270325 title "Pd-Catalyzed Regioselective Arylation on the C-5 Position of<i>N</i>-Aryl 1,2,3-Triazoles" @default.
- W2314270325 cites W1702491069 @default.
- W2314270325 cites W1964615244 @default.
- W2314270325 cites W1966182479 @default.
- W2314270325 cites W1968652549 @default.
- W2314270325 cites W1971275758 @default.
- W2314270325 cites W1974221324 @default.
- W2314270325 cites W1975708211 @default.
- W2314270325 cites W1977851521 @default.
- W2314270325 cites W1980934047 @default.
- W2314270325 cites W1987207730 @default.
- W2314270325 cites W1995270643 @default.
- W2314270325 cites W1998423202 @default.
- W2314270325 cites W2000128109 @default.
- W2314270325 cites W2006758620 @default.
- W2314270325 cites W2013681136 @default.
- W2314270325 cites W2014767176 @default.
- W2314270325 cites W2015516088 @default.
- W2314270325 cites W2016351523 @default.
- W2314270325 cites W2021617112 @default.
- W2314270325 cites W2025004555 @default.
- W2314270325 cites W2028959324 @default.
- W2314270325 cites W2035696398 @default.
- W2314270325 cites W2037499890 @default.
- W2314270325 cites W2039738410 @default.
- W2314270325 cites W2044490585 @default.
- W2314270325 cites W2049477866 @default.
- W2314270325 cites W2049800012 @default.
- W2314270325 cites W2052948087 @default.
- W2314270325 cites W2053988248 @default.
- W2314270325 cites W2058886486 @default.
- W2314270325 cites W2063128491 @default.
- W2314270325 cites W2068617439 @default.
- W2314270325 cites W2068644789 @default.
- W2314270325 cites W2075381847 @default.
- W2314270325 cites W2077805528 @default.
- W2314270325 cites W2077975645 @default.
- W2314270325 cites W2081540483 @default.
- W2314270325 cites W2087624831 @default.
- W2314270325 cites W2089100356 @default.
- W2314270325 cites W2089427958 @default.
- W2314270325 cites W2090452315 @default.
- W2314270325 cites W2091897182 @default.
- W2314270325 cites W2092688690 @default.
- W2314270325 cites W2097184152 @default.
- W2314270325 cites W2110498029 @default.
- W2314270325 cites W2112206201 @default.
- W2314270325 cites W2120991237 @default.
- W2314270325 cites W2142868818 @default.
- W2314270325 cites W2145662716 @default.
- W2314270325 cites W2146561272 @default.
- W2314270325 cites W2150697053 @default.
- W2314270325 cites W2152083435 @default.
- W2314270325 cites W2159688044 @default.
- W2314270325 cites W2162586071 @default.
- W2314270325 cites W2163710386 @default.
- W2314270325 cites W2316321048 @default.
- W2314270325 cites W2328719349 @default.
- W2314270325 cites W2342610272 @default.
- W2314270325 cites W2949123589 @default.
- W2314270325 cites W2949484111 @default.
- W2314270325 cites W2949551318 @default.
- W2314270325 cites W2950206052 @default.
- W2314270325 cites W2950431354 @default.
- W2314270325 cites W2950884776 @default.
- W2314270325 cites W2952967879 @default.
- W2314270325 cites W4237374233 @default.
- W2314270325 cites W4237738536 @default.
- W2314270325 cites W4241812539 @default.
- W2314270325 doi "https://doi.org/10.1021/jo5026145" @default.
- W2314270325 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25710598" @default.
- W2314270325 hasPublicationYear "2015" @default.
- W2314270325 type Work @default.
- W2314270325 sameAs 2314270325 @default.
- W2314270325 citedByCount "31" @default.
- W2314270325 countsByYear W23142703252015 @default.
- W2314270325 countsByYear W23142703252016 @default.
- W2314270325 countsByYear W23142703252017 @default.
- W2314270325 countsByYear W23142703252018 @default.
- W2314270325 countsByYear W23142703252019 @default.
- W2314270325 countsByYear W23142703252020 @default.
- W2314270325 countsByYear W23142703252021 @default.
- W2314270325 countsByYear W23142703252022 @default.
- W2314270325 crossrefType "journal-article" @default.
- W2314270325 hasAuthorship W2314270325A5049314202 @default.
- W2314270325 hasAuthorship W2314270325A5050261459 @default.
- W2314270325 hasAuthorship W2314270325A5053675041 @default.
- W2314270325 hasConcept C155647269 @default.
- W2314270325 hasConcept C161790260 @default.
- W2314270325 hasConcept C178790620 @default.
- W2314270325 hasConcept C185592680 @default.