Matches in SemOpenAlex for { <https://semopenalex.org/work/W2314461111> ?p ?o ?g. }
- W2314461111 endingPage "2186" @default.
- W2314461111 startingPage "2183" @default.
- W2314461111 abstract "Candida albicans is the most common fungal pathogen in humans, and most diseases produced by C. albicans are associated with biofilms. We previously developed nylon-3 polymers with potent activity against planktonic C. albicans and excellent C. albicans versus mammalian cell selectivity. Here we show that these nylon-3 polymers have strong and selective activity against drug-resistant C. albicans in biofilms, as manifested by inhibition of biofilm formation and by killing of C. albicans in mature biofilms. The best nylon-3 polymer (poly-βNM) is superior to the antifungal drug fluconazole for all three strains examined. This polymer is slightly less effective than amphotericin B (AmpB) for two strains, but the polymer is superior against an AmpB-resistant strain." @default.
- W2314461111 created "2016-06-24" @default.
- W2314461111 creator A5016484148 @default.
- W2314461111 creator A5023192029 @default.
- W2314461111 creator A5028362782 @default.
- W2314461111 creator A5044989625 @default.
- W2314461111 creator A5045129810 @default.
- W2314461111 creator A5056518614 @default.
- W2314461111 date "2015-02-04" @default.
- W2314461111 modified "2023-10-01" @default.
- W2314461111 title "Nylon-3 Polymers Active against Drug-Resistant <i>Candida albicans</i> Biofilms" @default.
- W2314461111 cites W1501359805 @default.
- W2314461111 cites W1531531679 @default.
- W2314461111 cites W1964581982 @default.
- W2314461111 cites W1971374993 @default.
- W2314461111 cites W1975128800 @default.
- W2314461111 cites W1976988207 @default.
- W2314461111 cites W1984081181 @default.
- W2314461111 cites W1988884953 @default.
- W2314461111 cites W1992124313 @default.
- W2314461111 cites W1994881882 @default.
- W2314461111 cites W1997152791 @default.
- W2314461111 cites W1999876290 @default.
- W2314461111 cites W2012050459 @default.
- W2314461111 cites W2027843124 @default.
- W2314461111 cites W2039795845 @default.
- W2314461111 cites W2047190660 @default.
- W2314461111 cites W2050140989 @default.
- W2314461111 cites W2054354538 @default.
- W2314461111 cites W2054602599 @default.
- W2314461111 cites W2059111198 @default.
- W2314461111 cites W2073477477 @default.
- W2314461111 cites W2078424893 @default.
- W2314461111 cites W2083981420 @default.
- W2314461111 cites W2087043215 @default.
- W2314461111 cites W2093904878 @default.
- W2314461111 cites W2094138644 @default.
- W2314461111 cites W2094210743 @default.
- W2314461111 cites W2094446407 @default.
- W2314461111 cites W2098368706 @default.
- W2314461111 cites W2100193182 @default.
- W2314461111 cites W2101027851 @default.
- W2314461111 cites W2107794472 @default.
- W2314461111 cites W2110892287 @default.
- W2314461111 cites W2130763979 @default.
- W2314461111 cites W2131380952 @default.
- W2314461111 cites W2132879359 @default.
- W2314461111 cites W2140173686 @default.
- W2314461111 cites W2142665028 @default.
- W2314461111 cites W2156322493 @default.
- W2314461111 cites W2160780417 @default.
- W2314461111 cites W2161508942 @default.
- W2314461111 cites W2167658541 @default.
- W2314461111 cites W2167756658 @default.
- W2314461111 cites W2321033437 @default.
- W2314461111 cites W2324852070 @default.
- W2314461111 cites W2328059730 @default.
- W2314461111 cites W2474169068 @default.
- W2314461111 cites W4246732698 @default.
- W2314461111 doi "https://doi.org/10.1021/ja512567y" @default.
- W2314461111 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4682891" @default.
- W2314461111 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25650957" @default.
- W2314461111 hasPublicationYear "2015" @default.
- W2314461111 type Work @default.
- W2314461111 sameAs 2314461111 @default.
- W2314461111 citedByCount "117" @default.
- W2314461111 countsByYear W23144611112015 @default.
- W2314461111 countsByYear W23144611112016 @default.
- W2314461111 countsByYear W23144611112017 @default.
- W2314461111 countsByYear W23144611112018 @default.
- W2314461111 countsByYear W23144611112019 @default.
- W2314461111 countsByYear W23144611112020 @default.
- W2314461111 countsByYear W23144611112021 @default.
- W2314461111 countsByYear W23144611112022 @default.
- W2314461111 countsByYear W23144611112023 @default.
- W2314461111 crossrefType "journal-article" @default.
- W2314461111 hasAuthorship W2314461111A5016484148 @default.
- W2314461111 hasAuthorship W2314461111A5023192029 @default.
- W2314461111 hasAuthorship W2314461111A5028362782 @default.
- W2314461111 hasAuthorship W2314461111A5044989625 @default.
- W2314461111 hasAuthorship W2314461111A5045129810 @default.
- W2314461111 hasAuthorship W2314461111A5056518614 @default.
- W2314461111 hasBestOaLocation W23144611112 @default.
- W2314461111 hasConcept C145081991 @default.
- W2314461111 hasConcept C185592680 @default.
- W2314461111 hasConcept C2779548794 @default.
- W2314461111 hasConcept C2779629538 @default.
- W2314461111 hasConcept C2780035454 @default.
- W2314461111 hasConcept C2780651595 @default.
- W2314461111 hasConcept C2780917455 @default.
- W2314461111 hasConcept C2991737395 @default.
- W2314461111 hasConcept C523546767 @default.
- W2314461111 hasConcept C54355233 @default.
- W2314461111 hasConcept C58123911 @default.
- W2314461111 hasConcept C86803240 @default.
- W2314461111 hasConcept C89423630 @default.
- W2314461111 hasConcept C98274493 @default.
- W2314461111 hasConceptScore W2314461111C145081991 @default.