Matches in SemOpenAlex for { <https://semopenalex.org/work/W2314492798> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2314492798 endingPage "18" @default.
- W2314492798 startingPage "17" @default.
- W2314492798 abstract "Several years ago, one of us, in a clinical study of asthma in children, felt that there was strong evidence for the idea that asthma may be an “acquired” disease, and in some cases the result of sensitization through the nasal route. Insofar as it is impossible to study the mechanism of this condition in the human being, we have applied our hypotheses to direct investigation in the guinea pig. This animal was chosen for our experiments because of the ease with which respiratory anaphylactic phenomena can be elicited. We have found certain corroborative evidence for our results in the works of Busson and Ogata, Friedberger, Peragnani, Sewall and Powell, and Giani. 1. Guinea pigs were sensitized by exposing them to the dust of dried horse dander; subsequent intravenous injection of a protein extract of this same horse dander caused death. 2. Animals sensitized by giving them intraperitoneal injections of horse dander extract have subsequently shown grave anaphylactic phenomena and, also acute anaphylactic death when exposed to horse dander dust. 3. Animals sensitized by exposing them to horse dander subsequently exhibited marked respiratory anaphylactic phenomena when subjected to the same horse dander dust. This latter group of animals, which at no time had received parenteral injections of the protein extract of horse dander, have presented symptoms that are comparable to the bronchial asthma of human beings. These guinea pigs have come in contact with the horse dander dust in the same manner that a human being might, for at no time was the horse dander forcibly injected into their nares. Several animals that had previously been sensitized by an intraperitoneal injection of horse dander, died within two to four minutes after having been put in the cage containing circulating horse dander dust." @default.
- W2314492798 created "2016-06-24" @default.
- W2314492798 creator A5004087630 @default.
- W2314492798 creator A5051704666 @default.
- W2314492798 creator A5057974987 @default.
- W2314492798 date "1925-10-01" @default.
- W2314492798 modified "2023-09-25" @default.
- W2314492798 title "Nasal sensitization, nasal anaphylactic shock and respiratory symptoms simulating bronchial asthma, in the guinea pig." @default.
- W2314492798 doi "https://doi.org/10.3181/00379727-23-2807" @default.
- W2314492798 hasPublicationYear "1925" @default.
- W2314492798 type Work @default.
- W2314492798 sameAs 2314492798 @default.
- W2314492798 citedByCount "8" @default.
- W2314492798 crossrefType "journal-article" @default.
- W2314492798 hasAuthorship W2314492798A5004087630 @default.
- W2314492798 hasAuthorship W2314492798A5051704666 @default.
- W2314492798 hasAuthorship W2314492798A5057974987 @default.
- W2314492798 hasConcept C126322002 @default.
- W2314492798 hasConcept C151730666 @default.
- W2314492798 hasConcept C203014093 @default.
- W2314492798 hasConcept C207480886 @default.
- W2314492798 hasConcept C2775933838 @default.
- W2314492798 hasConcept C2776042228 @default.
- W2314492798 hasConcept C2776217527 @default.
- W2314492798 hasConcept C2778815084 @default.
- W2314492798 hasConcept C2780510475 @default.
- W2314492798 hasConcept C2780762169 @default.
- W2314492798 hasConcept C2994163677 @default.
- W2314492798 hasConcept C71924100 @default.
- W2314492798 hasConcept C74962801 @default.
- W2314492798 hasConcept C86803240 @default.
- W2314492798 hasConceptScore W2314492798C126322002 @default.
- W2314492798 hasConceptScore W2314492798C151730666 @default.
- W2314492798 hasConceptScore W2314492798C203014093 @default.
- W2314492798 hasConceptScore W2314492798C207480886 @default.
- W2314492798 hasConceptScore W2314492798C2775933838 @default.
- W2314492798 hasConceptScore W2314492798C2776042228 @default.
- W2314492798 hasConceptScore W2314492798C2776217527 @default.
- W2314492798 hasConceptScore W2314492798C2778815084 @default.
- W2314492798 hasConceptScore W2314492798C2780510475 @default.
- W2314492798 hasConceptScore W2314492798C2780762169 @default.
- W2314492798 hasConceptScore W2314492798C2994163677 @default.
- W2314492798 hasConceptScore W2314492798C71924100 @default.
- W2314492798 hasConceptScore W2314492798C74962801 @default.
- W2314492798 hasConceptScore W2314492798C86803240 @default.
- W2314492798 hasIssue "1" @default.
- W2314492798 hasLocation W23144927981 @default.
- W2314492798 hasOpenAccess W2314492798 @default.
- W2314492798 hasPrimaryLocation W23144927981 @default.
- W2314492798 hasRelatedWork W1761207137 @default.
- W2314492798 hasRelatedWork W1840396327 @default.
- W2314492798 hasRelatedWork W1992480592 @default.
- W2314492798 hasRelatedWork W2044541967 @default.
- W2314492798 hasRelatedWork W2314492798 @default.
- W2314492798 hasRelatedWork W2333078550 @default.
- W2314492798 hasRelatedWork W2748348003 @default.
- W2314492798 hasRelatedWork W3113114371 @default.
- W2314492798 hasRelatedWork W4313375442 @default.
- W2314492798 hasRelatedWork W2155366057 @default.
- W2314492798 hasVolume "23" @default.
- W2314492798 isParatext "false" @default.
- W2314492798 isRetracted "false" @default.
- W2314492798 magId "2314492798" @default.
- W2314492798 workType "article" @default.