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- W2314601975 endingPage "476" @default.
- W2314601975 startingPage "437" @default.
- W2314601975 abstract "Exposure to particulate matter (PM) from traffic vehicles is hazardous to the vascular system, leading to clinical manifestations and mortality due to ischemic heart disease. By analogy, nanomaterials may also be associated with the same outcomes. Here, the effects of exposure to PM from ambient air, diesel exhaust and certain nanomaterials on atherosclerosis and vasomotor function in animals have been assessed. The majority of studies have used pulmonary exposure by inhalation or instillation, although there are some studies on non-pulmonary routes such as the gastrointestinal tract. Airway exposure to air pollution particles and nanomaterials is associated with similar effects on atherosclerosis progression, augmented vasoconstriction and blunted vasorelaxation responses in arteries, whereas exposure to diesel exhaust is associated with lower responses. At present, there is no convincing evidence of dose-dependent effects across studies. Oxidative stress and inflammation have been observed in the arterial wall of PM-exposed animals with vasomotor dysfunction or plaque progression. From the data, it is evident that pulmonary and systemic inflammation does not seem to be necessary for these vascular effects to occur. Furthermore, there is inconsistent evidence with regard to altered plasma lipid profile and systemic inflammation as a key step in vasomotor dysfunction and progression of atherosclerosis in PM-exposed animals. In summary, the results show that certain nanomaterials, including TiO2, carbon black and carbon nanotubes, have similar hazards to the vascular system as combustion-derived PM." @default.
- W2314601975 created "2016-06-24" @default.
- W2314601975 creator A5021170936 @default.
- W2314601975 creator A5027983515 @default.
- W2314601975 creator A5034937943 @default.
- W2314601975 creator A5040002945 @default.
- W2314601975 creator A5046541271 @default.
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- W2314601975 creator A5054957111 @default.
- W2314601975 creator A5058796610 @default.
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- W2314601975 creator A5065683462 @default.
- W2314601975 creator A5071948535 @default.
- W2314601975 creator A5082772790 @default.
- W2314601975 date "2016-03-30" @default.
- W2314601975 modified "2023-10-16" @default.
- W2314601975 title "Atherosclerosis and vasomotor dysfunction in arteries of animals after exposure to combustion-derived particulate matter or nanomaterials" @default.
- W2314601975 cites W1492946553 @default.
- W2314601975 cites W1520348292 @default.
- W2314601975 cites W1564553363 @default.
- W2314601975 cites W1736633011 @default.
- W2314601975 cites W1825218498 @default.
- W2314601975 cites W1880310083 @default.
- W2314601975 cites W1932718020 @default.
- W2314601975 cites W1965631806 @default.
- W2314601975 cites W1969029151 @default.
- W2314601975 cites W1969148781 @default.
- W2314601975 cites W1971160571 @default.
- W2314601975 cites W1971543773 @default.
- W2314601975 cites W1973183366 @default.
- W2314601975 cites W1973558093 @default.
- W2314601975 cites W1977183031 @default.
- W2314601975 cites W1978884182 @default.
- W2314601975 cites W1979799510 @default.
- W2314601975 cites W1981175458 @default.
- W2314601975 cites W1981264056 @default.
- W2314601975 cites W1984803492 @default.
- W2314601975 cites W1985785997 @default.
- W2314601975 cites W1988737422 @default.
- W2314601975 cites W1990075095 @default.
- W2314601975 cites W1997756128 @default.
- W2314601975 cites W1998757682 @default.
- W2314601975 cites W1998844305 @default.
- W2314601975 cites W2003828176 @default.
- W2314601975 cites W2004075203 @default.
- W2314601975 cites W2005048980 @default.
- W2314601975 cites W2005147038 @default.
- W2314601975 cites W2006154698 @default.
- W2314601975 cites W2006857216 @default.
- W2314601975 cites W2006933992 @default.
- W2314601975 cites W2007037079 @default.
- W2314601975 cites W2007476356 @default.
- W2314601975 cites W2009011345 @default.
- W2314601975 cites W2011707607 @default.
- W2314601975 cites W2012128752 @default.
- W2314601975 cites W2014709188 @default.
- W2314601975 cites W2015911608 @default.
- W2314601975 cites W2016285140 @default.
- W2314601975 cites W2017887957 @default.
- W2314601975 cites W2018294565 @default.
- W2314601975 cites W2018873398 @default.
- W2314601975 cites W2019300253 @default.
- W2314601975 cites W2021734102 @default.
- W2314601975 cites W2022320640 @default.
- W2314601975 cites W2022647234 @default.
- W2314601975 cites W2025047972 @default.
- W2314601975 cites W2025203583 @default.
- W2314601975 cites W2026225722 @default.
- W2314601975 cites W2027843899 @default.
- W2314601975 cites W2027914973 @default.
- W2314601975 cites W2029456383 @default.
- W2314601975 cites W2032611951 @default.
- W2314601975 cites W2036397284 @default.
- W2314601975 cites W2036967608 @default.
- W2314601975 cites W2037371398 @default.
- W2314601975 cites W2037904994 @default.
- W2314601975 cites W2038286460 @default.
- W2314601975 cites W2038823475 @default.
- W2314601975 cites W2040228345 @default.
- W2314601975 cites W2040592634 @default.
- W2314601975 cites W2041008292 @default.
- W2314601975 cites W2041515611 @default.
- W2314601975 cites W2041692988 @default.
- W2314601975 cites W2047047744 @default.
- W2314601975 cites W2048688104 @default.
- W2314601975 cites W2049928792 @default.
- W2314601975 cites W2051909759 @default.
- W2314601975 cites W2052436262 @default.
- W2314601975 cites W2055212297 @default.
- W2314601975 cites W2055984108 @default.
- W2314601975 cites W2056078688 @default.
- W2314601975 cites W2058410117 @default.
- W2314601975 cites W2060350590 @default.
- W2314601975 cites W2060809302 @default.
- W2314601975 cites W2061997886 @default.
- W2314601975 cites W2064676700 @default.
- W2314601975 cites W2067471064 @default.
- W2314601975 cites W2070485543 @default.