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- W2314885761 endingPage "355" @default.
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- W2314885761 abstract "Plasma free fatty acids (non-esterified fatty acids) increase in the first hour of the onset of acute myocardial ischaemia. This results from catecholamine stimulation of adipose tissue lipolysis. It can lead to a metabolic crisis in the injured myocardium with the development of ventricular arrhythmias and increased early mortality. Preconditioning, β-adrenergic blockade and glucose–insulin–potassium are possible therapeutic approaches, but anti-lipolytic agents, such as some nicotinic acid derivatives, can reduce plasma free fatty acid concentrations within minutes and have untried potential. A clinical trial of their effectiveness is needed from the first moment when a patient with an acute coronary syndrome is seen by paramedics." @default.
- W2314885761 created "2016-06-24" @default.
- W2314885761 creator A5037603331 @default.
- W2314885761 date "2014-11-28" @default.
- W2314885761 modified "2023-09-25" @default.
- W2314885761 title "Fatty acids and the risk of death during acute myocardial ischaemia" @default.
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- W2314885761 doi "https://doi.org/10.1042/cs20140404" @default.
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