Matches in SemOpenAlex for { <https://semopenalex.org/work/W2314922680> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2314922680 endingPage "S8" @default.
- W2314922680 startingPage "S1" @default.
- W2314922680 abstract "Summary: Data on a twice-daily dosage schedule with moclobemide in the treatment of depression is limited. In this study, moclobemide 150 mg twice daily (b.i.d.) was compared to two different three-times-daily (t.i.d.) regimens with total daily dosages of 300 and 450 mg, respectively, over a 6-week period. The study was randomized, double-blind, and conducted at three university centers. Efficacy was measured on the Hamilton Depression and Anxiety Rating Scales, on the Zung Scale, and on clinical global impression. Tolerability and safety were assessed through adverse events and vital signs and on clinical global impression. One hundred seventy-eight depressed outpatients were included, and 158 completed the study. The treatment groups were comparable at baseline. No clear differences between the treatment groups could be shown with respect to efficacy. There was, however, a slightly larger decrease in the total HAM-A score in the groups receiving 150 mg b.i.d. and t.i.d. than in the third group. There were no marked differences between the groups with respect to tolerability and safety. Tolerability was rated “good” or “excellent” in 94% of patients, and there was no appreciable change in vital signs in any of the treatment groups. Moclobemide 150 mg b.i.d. is the optimal initial schedule for treatment of depression." @default.
- W2314922680 created "2016-06-24" @default.
- W2314922680 creator A5014079208 @default.
- W2314922680 creator A5051616339 @default.
- W2314922680 creator A5071142012 @default.
- W2314922680 creator A5075482338 @default.
- W2314922680 date "1994-01-01" @default.
- W2314922680 modified "2023-10-16" @default.
- W2314922680 title "Moclobemide Twice Daily in the Treatment of Major Depressive Episode: A Double-Blind, Multicenter Comparison with Different Three-Times-Daily Dosage Schedules" @default.
- W2314922680 doi "https://doi.org/10.1097/00002826-199417001-00002" @default.
- W2314922680 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7954480" @default.
- W2314922680 hasPublicationYear "1994" @default.
- W2314922680 type Work @default.
- W2314922680 sameAs 2314922680 @default.
- W2314922680 citedByCount "3" @default.
- W2314922680 countsByYear W23149226802023 @default.
- W2314922680 crossrefType "journal-article" @default.
- W2314922680 hasAuthorship W2314922680A5014079208 @default.
- W2314922680 hasAuthorship W2314922680A5051616339 @default.
- W2314922680 hasAuthorship W2314922680A5071142012 @default.
- W2314922680 hasAuthorship W2314922680A5075482338 @default.
- W2314922680 hasConcept C118552586 @default.
- W2314922680 hasConcept C126322002 @default.
- W2314922680 hasConcept C142724271 @default.
- W2314922680 hasConcept C15744967 @default.
- W2314922680 hasConcept C162156334 @default.
- W2314922680 hasConcept C197934379 @default.
- W2314922680 hasConcept C204787440 @default.
- W2314922680 hasConcept C27081682 @default.
- W2314922680 hasConcept C2776000289 @default.
- W2314922680 hasConcept C2776890885 @default.
- W2314922680 hasConcept C2778375690 @default.
- W2314922680 hasConcept C2779177272 @default.
- W2314922680 hasConcept C2780237459 @default.
- W2314922680 hasConcept C2780580376 @default.
- W2314922680 hasConcept C42219234 @default.
- W2314922680 hasConcept C535046627 @default.
- W2314922680 hasConcept C558461103 @default.
- W2314922680 hasConcept C71924100 @default.
- W2314922680 hasConceptScore W2314922680C118552586 @default.
- W2314922680 hasConceptScore W2314922680C126322002 @default.
- W2314922680 hasConceptScore W2314922680C142724271 @default.
- W2314922680 hasConceptScore W2314922680C15744967 @default.
- W2314922680 hasConceptScore W2314922680C162156334 @default.
- W2314922680 hasConceptScore W2314922680C197934379 @default.
- W2314922680 hasConceptScore W2314922680C204787440 @default.
- W2314922680 hasConceptScore W2314922680C27081682 @default.
- W2314922680 hasConceptScore W2314922680C2776000289 @default.
- W2314922680 hasConceptScore W2314922680C2776890885 @default.
- W2314922680 hasConceptScore W2314922680C2778375690 @default.
- W2314922680 hasConceptScore W2314922680C2779177272 @default.
- W2314922680 hasConceptScore W2314922680C2780237459 @default.
- W2314922680 hasConceptScore W2314922680C2780580376 @default.
- W2314922680 hasConceptScore W2314922680C42219234 @default.
- W2314922680 hasConceptScore W2314922680C535046627 @default.
- W2314922680 hasConceptScore W2314922680C558461103 @default.
- W2314922680 hasConceptScore W2314922680C71924100 @default.
- W2314922680 hasLocation W23149226801 @default.
- W2314922680 hasLocation W23149226802 @default.
- W2314922680 hasOpenAccess W2314922680 @default.
- W2314922680 hasPrimaryLocation W23149226801 @default.
- W2314922680 hasRelatedWork W1966047811 @default.
- W2314922680 hasRelatedWork W2003290789 @default.
- W2314922680 hasRelatedWork W2007100542 @default.
- W2314922680 hasRelatedWork W2091216391 @default.
- W2314922680 hasRelatedWork W2312405883 @default.
- W2314922680 hasRelatedWork W2314922680 @default.
- W2314922680 hasRelatedWork W2331460178 @default.
- W2314922680 hasRelatedWork W2393784267 @default.
- W2314922680 hasRelatedWork W2394317912 @default.
- W2314922680 hasRelatedWork W37966026 @default.
- W2314922680 hasVolume "17" @default.
- W2314922680 isParatext "false" @default.
- W2314922680 isRetracted "false" @default.
- W2314922680 magId "2314922680" @default.
- W2314922680 workType "article" @default.