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- W2314970057 abstract "Introduction: GLP-1 and GIP mediate the incretin effect (IE), i.e. the difference between meal-induced insulin secretion and insulinemia during an isoglycemic glucose infusion. These gut hormones are rapidly inactivated by DPP-4 and inhibition of this enzyme lowers hyperglycemia. However, the role of endogenous GLP-1 and mechanisms of DPP-4 inhibition are incompletely understood. We examined the anti-diabetic effects of GLP-1 using its receptor antagonist exendin (9 – 39) (Ex-9) with or without concomitant DPP-4 inhibition." @default.
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- W2314970057 date "2014-03-05" @default.
- W2314970057 modified "2023-10-18" @default.
- W2314970057 title "The role of GLP-1 in type 2 diabetes (T2D): effects of DPP-4 inhibition and GLP-1 receptor blockade" @default.
- W2314970057 doi "https://doi.org/10.1055/s-0034-1372117" @default.
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