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- W2314972698 abstract "The predominant limitation on the broader application of clinical transplantation is the inadequate number of donor organs available. A coordinated policy for maximizing donor yield is essential. Central to this aim is the minimization of organ loss to the pathophysiologic ravages of brainstem death. This article briefly reviews the pathophysiology of brain death, with particular emphasis on efforts to resuscitate unstable donors and use “marginal” organs. A growing body of evidence shows that the rapid physiologic decline seen after brainstem death can be stabilized by active donor resuscitation. The evidence supporting and opposing the various donor management therapies is considered here briefly. Current controversies are examined in light of recent experimental evidence." @default.
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- W2314972698 date "1999-06-01" @default.
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- W2314972698 title "Aggressive donor management" @default.
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- W2314972698 doi "https://doi.org/10.1097/00075200-199906000-00005" @default.
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