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- W2314974879 abstract "The blood group A antigen has been reported to exist on all blood cells's surface. However, the recent studies using the new immunological methods concluded that the A antigen could not be detected on neutrophils and monocytes.Then we examined the presence of the A antigen on granulocytes, lymphocytes, monocytes, platelets and megakaryocytes using the mouse anti-A monoclonal antibody and the avidin-biotin peroxidase complex (ABC) method.By this method the A antigen could not be detected on neutrophils, eosinophils, basophils and monocytes.The A antigen was weakly detected on lymphocytes from the group A secretor [Le(a-b+)], but not on lymphocytes from the non-secretor [Le(a+b-)]. The result indicated the A antigen (type 1H chain) on lymphocytes might be derived from the plasma. In contrast, the A antigen was strongly expressed on platelets, regardless of the A secretor status (type 1H chain, type 2H chain). Nevertheless, megakaryocytes which were the precursor cells of platelets, had no expression of the A antigens on the surfaces. We must consider when and how the A antigen on the surfaces of platelets come into existence." @default.
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- W2314974879 date "1987-01-01" @default.
- W2314974879 modified "2023-10-17" @default.
- W2314974879 title "Detection of blood group A antigen on human blood cells using the avidin-biotin peroxidase complex(ABC) method." @default.
- W2314974879 doi "https://doi.org/10.3925/jjtc1958.33.233" @default.
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