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- W2315145280 endingPage "593" @default.
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- W2315145280 abstract "Background: Animals and animal toxins have a long-lasting tradition in diverse human cultures all over the world. In addition to medicinal plants, animals are important components of many traditional medicines. Methods: By using selected examples, we give an overview of animals, animal toxins, and derivatives to illustrate their pharmacological and therapeutic potential and use. Results: Animals have been used in traditional and modern medicines for treatment purposes. Medicinal leeches (Hirudo medicinalis) are applied for microsurgical operations and for prevention of tissue necrosis due to congestion and insufficient supply of blood capillaries. Patches of blister beetles (Cantharis vesicatoria) have been topically applied in China since centuries against warts and poxvirus-caused molluscum contagiosum. Snake venoms are a rich source for drug development. Some examples are batroxobin (reptilase) from Bothrops moujeni and B. atrox, and others. Bioactive peptides have also been identified from spider and scorpion venoms such as GsMTx-4 from the Chilean rose Tarantula (Grammostola spatulata) or chlorotoxin from the Yellow Israeli scorpion (Leiurus quinquestriatus quinquestriatus). Amphibian venoms have frequently been used as arrow poisons by indigenous tribes. The marine biodiversity is also a rich resource for new drugs. A large array of toxins can be found in sea snails. Important examples are ωconotoxin from Conus purpurascens, contukalin-G from C. geographus, and ACV1 from Review Article British Journal of Applied Science & Technology, 4(4): 578-593, 2014 579 C. victoriae. Examples among many others are aplidine from Aplidium albicans, pseudopterosin from the Pseudopterogorgia genus, and dolastatin from Dolabella auricularia. Conclusion: Animals or compounds isolated from snake, spider or scorpion venoms, frog toxins, and toxins from marine organisms reveal astonishing pharmacological activities. Cross-disciplinary approaches between organic and medicinal chemistry, pharmacology, toxicology, molecular biology, and medicine are required to explore the full potential of animal toxins and their derivatives as important candidates in the drug development pipeline." @default.
- W2315145280 created "2016-06-24" @default.
- W2315145280 creator A5008559060 @default.
- W2315145280 date "2014-01-10" @default.
- W2315145280 modified "2023-09-30" @default.
- W2315145280 title "Animals and Animal Toxins in Traditional and Modern Medicine" @default.
- W2315145280 cites W1029446489 @default.
- W2315145280 cites W1531951525 @default.
- W2315145280 cites W1578487703 @default.
- W2315145280 cites W185865660 @default.
- W2315145280 cites W1969495311 @default.
- W2315145280 cites W1970761653 @default.
- W2315145280 cites W1973120576 @default.
- W2315145280 cites W1974182196 @default.
- W2315145280 cites W1974213388 @default.
- W2315145280 cites W1974699550 @default.
- W2315145280 cites W1975090409 @default.
- W2315145280 cites W1977106917 @default.
- W2315145280 cites W1982409583 @default.
- W2315145280 cites W1987213013 @default.
- W2315145280 cites W1989269073 @default.
- W2315145280 cites W1989299599 @default.
- W2315145280 cites W1989352229 @default.
- W2315145280 cites W1991333067 @default.
- W2315145280 cites W1992126189 @default.
- W2315145280 cites W1995022664 @default.
- W2315145280 cites W1998347864 @default.
- W2315145280 cites W2001651711 @default.
- W2315145280 cites W2002777933 @default.
- W2315145280 cites W2003795585 @default.
- W2315145280 cites W2008669667 @default.
- W2315145280 cites W2011300030 @default.
- W2315145280 cites W2014923137 @default.
- W2315145280 cites W2016608967 @default.
- W2315145280 cites W2017640331 @default.
- W2315145280 cites W2018062375 @default.
- W2315145280 cites W2020004369 @default.
- W2315145280 cites W2023104686 @default.
- W2315145280 cites W2023300256 @default.
- W2315145280 cites W2024110554 @default.
- W2315145280 cites W2026192838 @default.
- W2315145280 cites W2030309070 @default.
- W2315145280 cites W2033089404 @default.
- W2315145280 cites W2035841324 @default.
- W2315145280 cites W2037140904 @default.
- W2315145280 cites W2039841798 @default.
- W2315145280 cites W2044727164 @default.
- W2315145280 cites W2046145831 @default.
- W2315145280 cites W2046311805 @default.
- W2315145280 cites W2047342401 @default.
- W2315145280 cites W2047439107 @default.
- W2315145280 cites W2048013243 @default.
- W2315145280 cites W2052604598 @default.
- W2315145280 cites W2052731599 @default.
- W2315145280 cites W2052921411 @default.
- W2315145280 cites W2059228484 @default.
- W2315145280 cites W2060633688 @default.
- W2315145280 cites W2062713415 @default.
- W2315145280 cites W2064100374 @default.
- W2315145280 cites W2065221724 @default.
- W2315145280 cites W2066518618 @default.
- W2315145280 cites W2072619059 @default.
- W2315145280 cites W2080206699 @default.
- W2315145280 cites W2081866319 @default.
- W2315145280 cites W2083033039 @default.
- W2315145280 cites W2083197307 @default.
- W2315145280 cites W2083707819 @default.
- W2315145280 cites W2084971410 @default.
- W2315145280 cites W2085120751 @default.
- W2315145280 cites W2086916208 @default.
- W2315145280 cites W2087797970 @default.
- W2315145280 cites W2088694924 @default.
- W2315145280 cites W2089176402 @default.
- W2315145280 cites W2089865016 @default.
- W2315145280 cites W2095130093 @default.
- W2315145280 cites W2112610666 @default.
- W2315145280 cites W2116294708 @default.
- W2315145280 cites W2135923112 @default.
- W2315145280 cites W2140222552 @default.
- W2315145280 cites W2141232732 @default.
- W2315145280 cites W2142445440 @default.
- W2315145280 cites W2144157240 @default.
- W2315145280 cites W2147263214 @default.
- W2315145280 cites W2150814653 @default.
- W2315145280 cites W2151888807 @default.
- W2315145280 cites W2152056973 @default.
- W2315145280 cites W2156794442 @default.
- W2315145280 cites W2157202197 @default.
- W2315145280 cites W2159271917 @default.
- W2315145280 cites W2159749344 @default.
- W2315145280 cites W2160386479 @default.
- W2315145280 cites W2161138188 @default.
- W2315145280 cites W2162463986 @default.
- W2315145280 cites W2166400462 @default.
- W2315145280 cites W2252830957 @default.
- W2315145280 cites W2327808590 @default.
- W2315145280 cites W2394792557 @default.
- W2315145280 cites W2418094786 @default.