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• W2315186744 startingPage "709" @default.
• W2315186744 abstract "Fertility in women is regulated by a series of highly coordinated and synchronized interactions in the hypothalamic–pituitary–ovarian axis (Figure 1A). The central regulator of the axis is the group of neurons that secrete gonadotropin-releasing hormone (GnRH).1 Their cell bodies reside in the arcuate nucleus, and their exons terminate in the median eminence near the hypothalamic–pituitary portal vasculature. These neurons are unique in that they have an intrinsic firing frequency such that GnRH is secreted in pulses at 60-to-90-minute intervals into the portal vasculature to be conveyed to the anterior pituitary gland. There GnRH binds to specific cell-surface receptors on the . . ." @default.
• W2315186744 created "2016-06-24" @default.
• W2315186744 creator A5056739025 @default.
• W2315186744 creator A5086044543 @default.
• W2315186744 date "1999-03-04" @default.
• W2315186744 modified "2023-10-17" @default.
• W2315186744 title "Single-Gene Mutations Resulting in Reproductive Dysfunction in Women" @default.
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• W2315186744 doi "https://doi.org/10.1056/nejm199903043400907" @default.
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• W2315186744 hasPublicationYear "1999" @default.
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