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- W2315216961 abstract "Among 683 patients who were registered to the All Japan Immunodeficiency Registry up to May 5, 1985 from 1975, twenty cases were reported to have developed malignant disease (s).The incidence of malignant diseases among these reported patients was approximately 3.3%, which was estimated about 500 times higher than general childhood populations. The patients with Chediak-Higashi syndrome showed the highest incidence of developing, malignant lymphoma_??_ (3 in 8 cases: 37.5%) and ataxia-telangiectasia was another immunodeficiency disease highly complicated with malignancy such as non-Hodgkin lymphoma, leukemias and cancers (7 in 51 patients: 13.7%).Our data seemed to show almost the same results to the reports from ICR except very low incidence of malignancy in Wiskott-Aldrich syndrome (only 1 in 45 cases: 2.2%)." @default.
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- W2315216961 date "1985-01-01" @default.
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- W2315216961 title "Primary immunodeficiency diseases and malignancy" @default.
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- W2315216961 doi "https://doi.org/10.2177/jsci.8.265" @default.
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