Matches in SemOpenAlex for { <https://semopenalex.org/work/W2315249170> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2315249170 endingPage "715" @default.
- W2315249170 startingPage "705" @default.
- W2315249170 abstract "When guinea pigs are fed cholesterol, the cholesterol content of their red cells increases progressively, a large number of cells become spurred, and a hemolytic anemia develops. Unesterified cholesterol is readily transferred from plasma, HDL, or LDL of cholesterol-fed, anemic guinea pigs to normal red cells in vitro. This transfer is reversible and is proportional to the concentration of unesterified cholesterol in the incubation medium. Red cells loaded in vitro with cholesterol develop spurs identical with those on red cells in the circulation of cholesterol-fed, anemic guinea pigs. Neither the cholesterol content nor the morphology of normal red cells is altered by incubation in control plasma or in concentrated control lipoproteins. Plasma infranates (d > 1.21 g/ml) of either group do not cause spurring of control red cells. We conclude: (a) that accumulation of cholesterol by guinea pig red cells in vitro requires an increased concentration of unesterified cholesterol in lipoprotein rather than an increased concentration of normal lipoproteins, and (b) that an increased cholesterol content in guinea pig red cell membranes is necessary for their abnormal morphology. The flux of cholesterol between cholesterol-loaded cells and plasma from cholesterol-fed guinea pigs is three times greater than that between control red cells and control plasma, and the fractional exchange rates are altered." @default.
- W2315249170 created "2016-06-24" @default.
- W2315249170 creator A5040740255 @default.
- W2315249170 creator A5045739061 @default.
- W2315249170 creator A5079546587 @default.
- W2315249170 date "1972-11-01" @default.
- W2315249170 modified "2023-10-18" @default.
- W2315249170 title "Effects of plasma lipoproteins from control and cholesterol-fed guinea pigs on red cell morphology and cholesterol content: an in vitro study" @default.
- W2315249170 cites W1500243384 @default.
- W2315249170 cites W1513897103 @default.
- W2315249170 cites W1775749144 @default.
- W2315249170 cites W1973885312 @default.
- W2315249170 cites W1980286536 @default.
- W2315249170 cites W1981393648 @default.
- W2315249170 cites W1984816665 @default.
- W2315249170 cites W1991147293 @default.
- W2315249170 cites W2003471749 @default.
- W2315249170 cites W2035576572 @default.
- W2315249170 cites W2052664734 @default.
- W2315249170 cites W2063316448 @default.
- W2315249170 cites W2066251930 @default.
- W2315249170 cites W2113504642 @default.
- W2315249170 cites W2118832530 @default.
- W2315249170 cites W2133694179 @default.
- W2315249170 cites W2168526937 @default.
- W2315249170 cites W2186595494 @default.
- W2315249170 cites W2214097981 @default.
- W2315249170 cites W2323304304 @default.
- W2315249170 cites W2345803541 @default.
- W2315249170 cites W2415137183 @default.
- W2315249170 cites W328883950 @default.
- W2315249170 doi "https://doi.org/10.1016/s0022-2275(20)39340-8" @default.
- W2315249170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4345053" @default.
- W2315249170 hasPublicationYear "1972" @default.
- W2315249170 type Work @default.
- W2315249170 sameAs 2315249170 @default.
- W2315249170 citedByCount "39" @default.
- W2315249170 countsByYear W23152491702016 @default.
- W2315249170 countsByYear W23152491702019 @default.
- W2315249170 crossrefType "journal-article" @default.
- W2315249170 hasAuthorship W2315249170A5040740255 @default.
- W2315249170 hasAuthorship W2315249170A5045739061 @default.
- W2315249170 hasAuthorship W2315249170A5079546587 @default.
- W2315249170 hasBestOaLocation W23152491701 @default.
- W2315249170 hasConcept C126322002 @default.
- W2315249170 hasConcept C134018914 @default.
- W2315249170 hasConcept C185592680 @default.
- W2315249170 hasConcept C202751555 @default.
- W2315249170 hasConcept C2778163477 @default.
- W2315249170 hasConcept C2778815084 @default.
- W2315249170 hasConcept C499950583 @default.
- W2315249170 hasConcept C55493867 @default.
- W2315249170 hasConcept C71924100 @default.
- W2315249170 hasConcept C86803240 @default.
- W2315249170 hasConcept C90856448 @default.
- W2315249170 hasConceptScore W2315249170C126322002 @default.
- W2315249170 hasConceptScore W2315249170C134018914 @default.
- W2315249170 hasConceptScore W2315249170C185592680 @default.
- W2315249170 hasConceptScore W2315249170C202751555 @default.
- W2315249170 hasConceptScore W2315249170C2778163477 @default.
- W2315249170 hasConceptScore W2315249170C2778815084 @default.
- W2315249170 hasConceptScore W2315249170C499950583 @default.
- W2315249170 hasConceptScore W2315249170C55493867 @default.
- W2315249170 hasConceptScore W2315249170C71924100 @default.
- W2315249170 hasConceptScore W2315249170C86803240 @default.
- W2315249170 hasConceptScore W2315249170C90856448 @default.
- W2315249170 hasIssue "6" @default.
- W2315249170 hasLocation W23152491701 @default.
- W2315249170 hasOpenAccess W2315249170 @default.
- W2315249170 hasPrimaryLocation W23152491701 @default.
- W2315249170 hasRelatedWork W1966504330 @default.
- W2315249170 hasRelatedWork W1979139803 @default.
- W2315249170 hasRelatedWork W2030889776 @default.
- W2315249170 hasRelatedWork W2035331946 @default.
- W2315249170 hasRelatedWork W2037631372 @default.
- W2315249170 hasRelatedWork W2040058909 @default.
- W2315249170 hasRelatedWork W2132898409 @default.
- W2315249170 hasRelatedWork W2149724265 @default.
- W2315249170 hasRelatedWork W2748952813 @default.
- W2315249170 hasRelatedWork W4249176446 @default.
- W2315249170 hasVolume "13" @default.
- W2315249170 isParatext "false" @default.
- W2315249170 isRetracted "false" @default.
- W2315249170 magId "2315249170" @default.
- W2315249170 workType "article" @default.