FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2315420811> ?p ?o ?g. }

• W2315420811 endingPage "386" @default.
• W2315420811 startingPage "381" @default.
• W2315420811 abstract "Objectives: Antrochoanal polyps (ACPs) originate from the inner wall of the maxillary sinus and either pass through the natural sinus ostia or cause pressure-induced destruction of the medial sinus wall. Eventually, they extend into the choanae and nasopharynx. Most authors who have studied the microstructure of ACPs, including the component stromal cells and surface epithelium, have not examined the transitional area between the sinus mucosa and the pedicle of the polyp. No explanation has been given for the absence of a cystic intrasinus portion of the polyp, in many cases refuting the therapy (most accepted) that polyps are caused by a mucous gland with a blocked acinus. We noted during endoscopic removal of the ACPs that the antral part of the polyp was cystic in only 5% of patients, and polypoid in 95%. The cystic intrasinus portion of the polyp is a cornerstone of the pathophysiology of ACPs, whether caused by inflammation, cicatrization, or allergy. This finding prompted us to examine the transitional area between the sinus mucosa and the pedicle of the polyp to verify the possibility that lymphatic obstruction—whether primary (areas of higher tissue pressure) or secondary (cicatrization or inflammation)—could be an etiologic factor in the formation of ACPs. Methods: The study material consisted of 25 ACPs and 25 chronic maxillary sinusitis mucosal biopsy specimens (control group). The detection of lymphatic vessels was based on the identification of lymph vessel endothelial hyaluronic acid receptor 1 (LYVE-1) in the endothelial cells of the lymphatic capillaries. This was the first lymph-specific hyaluronic acid receptor to be characterized, and is a uniquely powerful marker for lymph vessels, differentiating them from (blood) capillaries. Results: The density of the lymphatic vessels was marked in 22 of the 25 ACP specimens, ie, 88% of the ACP cases, compared with 16% of the control group. Conclusions: This study resulted in two main findings. The first was the absence of intramaxillary cysts in the ACPs in 23 cases (92%). The second was the markedly high density of lymphatic vessels in the transitional area between the sinus mucosa and the pedicle of the ACPs, in comparison with the density in the control group. These two findings refute the “blocked acinus theory” and indicate that lymphatic obstruction, whether primary or secondary to chronic sinus infection, might play a leading role in the formation and further growth of ACPs." @default.
• W2315420811 created "2016-06-24" @default.
• W2315420811 creator A5019679257 @default.
• W2315420811 creator A5043390515 @default.
• W2315420811 creator A5052855734 @default.
• W2315420811 creator A5068374818 @default.
• W2315420811 date "2014-03-04" @default.
• W2315420811 modified "2023-10-16" @default.
• W2315420811 title "Lymphatic Obstruction" @default.
• W2315420811 cites W1964570992 @default.
• W2315420811 cites W1964731772 @default.
• W2315420811 cites W1965909208 @default.
• W2315420811 cites W1977627080 @default.
• W2315420811 cites W1982511302 @default.
• W2315420811 cites W1984623524 @default.
• W2315420811 cites W2058073695 @default.
• W2315420811 cites W2062693558 @default.
• W2315420811 cites W2068881846 @default.
• W2315420811 cites W2071421485 @default.
• W2315420811 cites W2086845839 @default.
• W2315420811 cites W2102540823 @default.
• W2315420811 cites W2154554294 @default.
• W2315420811 cites W2201557378 @default.
• W2315420811 cites W2332693769 @default.
• W2315420811 cites W2414788149 @default.
• W2315420811 cites W2416026478 @default.
• W2315420811 cites W4231587321 @default.
• W2315420811 cites W47217765 @default.
• W2315420811 doi "https://doi.org/10.1177/0003489414522973" @default.
• W2315420811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24595626" @default.
• W2315420811 hasPublicationYear "2014" @default.
• W2315420811 type Work @default.
• W2315420811 sameAs 2315420811 @default.
• W2315420811 citedByCount "14" @default.
• W2315420811 countsByYear W23154208112015 @default.
• W2315420811 countsByYear W23154208112016 @default.
• W2315420811 countsByYear W23154208112018 @default.
• W2315420811 countsByYear W23154208112020 @default.
• W2315420811 countsByYear W23154208112021 @default.
• W2315420811 countsByYear W23154208112022 @default.
• W2315420811 countsByYear W23154208112023 @default.
• W2315420811 crossrefType "journal-article" @default.
• W2315420811 hasAuthorship W2315420811A5019679257 @default.
• W2315420811 hasAuthorship W2315420811A5043390515 @default.
• W2315420811 hasAuthorship W2315420811A5052855734 @default.
• W2315420811 hasAuthorship W2315420811A5068374818 @default.
• W2315420811 hasConcept C105702510 @default.
• W2315420811 hasConcept C121608353 @default.
• W2315420811 hasConcept C126322002 @default.
• W2315420811 hasConcept C142724271 @default.
• W2315420811 hasConcept C157369684 @default.
• W2315420811 hasConcept C16930146 @default.
• W2315420811 hasConcept C181152851 @default.
• W2315420811 hasConcept C2776407911 @default.
• W2315420811 hasConcept C2776914184 @default.
• W2315420811 hasConcept C2778705571 @default.
• W2315420811 hasConcept C2779013556 @default.
• W2315420811 hasConcept C2780965494 @default.
• W2315420811 hasConcept C59822182 @default.
• W2315420811 hasConcept C71924100 @default.
• W2315420811 hasConcept C86803240 @default.
• W2315420811 hasConceptScore W2315420811C105702510 @default.
• W2315420811 hasConceptScore W2315420811C121608353 @default.
• W2315420811 hasConceptScore W2315420811C126322002 @default.
• W2315420811 hasConceptScore W2315420811C142724271 @default.
• W2315420811 hasConceptScore W2315420811C157369684 @default.
• W2315420811 hasConceptScore W2315420811C16930146 @default.
• W2315420811 hasConceptScore W2315420811C181152851 @default.
• W2315420811 hasConceptScore W2315420811C2776407911 @default.
• W2315420811 hasConceptScore W2315420811C2776914184 @default.
• W2315420811 hasConceptScore W2315420811C2778705571 @default.
• W2315420811 hasConceptScore W2315420811C2779013556 @default.
• W2315420811 hasConceptScore W2315420811C2780965494 @default.
• W2315420811 hasConceptScore W2315420811C59822182 @default.
• W2315420811 hasConceptScore W2315420811C71924100 @default.
• W2315420811 hasConceptScore W2315420811C86803240 @default.
• W2315420811 hasIssue "6" @default.
• W2315420811 hasLocation W23154208111 @default.
• W2315420811 hasLocation W23154208112 @default.
• W2315420811 hasOpenAccess W2315420811 @default.
• W2315420811 hasPrimaryLocation W23154208111 @default.
• W2315420811 hasRelatedWork W2010709692 @default.
• W2315420811 hasRelatedWork W2076352248 @default.
• W2315420811 hasRelatedWork W2110925778 @default.
• W2315420811 hasRelatedWork W2119754704 @default.
• W2315420811 hasRelatedWork W2170270098 @default.
• W2315420811 hasRelatedWork W2244617787 @default.
• W2315420811 hasRelatedWork W2315420811 @default.
• W2315420811 hasRelatedWork W2345693209 @default.
• W2315420811 hasRelatedWork W2397024976 @default.
• W2315420811 hasRelatedWork W2189261883 @default.
• W2315420811 hasVolume "123" @default.
• W2315420811 isParatext "false" @default.
• W2315420811 isRetracted "false" @default.
• W2315420811 magId "2315420811" @default.
• W2315420811 workType "article" @default.