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- W2315428647 abstract "Purpose: To determine the risk of atrial fibrillation (AF) in individuals with diabetes mellitus (DM) compared with the background population. Methods: Longitudinal nationwide register based cohort study in a setting of inpatient and outpatient hospital care in Denmark from 1996 to 2010. The cohort included the entire Danish population aged between 18 and 100 years without prior DM and AF before 1996. Main outcome measures was rate of AF analysed by calculating incidence rates and by multivariable adjusted Poisson regression models. Results: Of 4,941,354 participants included in the cohort 312,166 were identified as having DM during follow up. A total of 197,529 including 19,368 with DM, was diagnosed as having AF during follow-up. The total incidence rate for AF was for participants without DM 2.58 (95% CI 2.57-2.59) per 1000 person years and for participants with DM 9.56 (95% CI 9.42-9.69), with especially high incidence rates among younger individuals with DM (Figure). In a multivariable Poisson regression analysis, adjusted for age, gender and comorbidity, the Incidence Rate Ratio for AF in individuals with diabetes was 1.69 (95% CI 1.67-1.72) compared with the background population. Incidence rates Non-DM, Participants without DM; DM, Participants with DM. Figure 1 Conclusion: DM was associated with substantially increased risk of AF, in particular among younger individuals. Strategies aimed at preventing AF early during the course of DM are warranted." @default.
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- W2315428647 date "2013-08-02" @default.
- W2315428647 modified "2023-09-26" @default.
- W2315428647 title "Diabetes is associated with doubling in risk of atrial fibrillation compared to the background population: a nationwide study" @default.
- W2315428647 doi "https://doi.org/10.1093/eurheartj/eht309.p4079" @default.
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