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• W2315473480 abstract "Considering the controversial results regarding the relationship between vitamin D levels and bone mineral density in different populations, the present study was designed to evaluate this correlation in a healthy Iranian population. Using a random cluster sample of apparently healthy men and women, this multicenter cross-sectional study was carried out among 4450 individuals living in urban areas of five major cities in Iran. Bone mineral density (BMD) values at different sites were analyzed along with the serum levels of 25(OH)D and PTH. Analysis of variance (ANOVA) was used to estimate the main effects, through comparing the mean values of these markers based on the bone mineral density status of the study group in each sex. 25(OH)D levels were inversely correlated with BMD values at total hip (r = −0.062 in men and r = −0.057 in women) and spine (r = −0.076 in men and r = −0.107 in women). After adjusting the data for age, the inverse correlation was no longer statistically significant. Serum 25(OH)D levels are inversely correlated with bone mass values in both sexes. Considerando os resultados controversos sobre a relação entre níveis de vitamina D e densidade mineral óssea em diferentes populações, o presente estudo foi desenhado para avaliar esta correlação em uma população iraniana saudável. Usando uma amostra aleatória de homens e mulheres aparentemente saudáveis, este estudo transversal multicêntrico considerou 4450 indivíduos que vivem em na região urbana de cinco grandes cidades no Irã. Os valores da densidade mineral óssea (DMO) foram analisados em conjunto com os níveis séricos de 25(OH)D e PTH. Análise da variação (ANOVA) foi utilizada para estimar os principais efeitos através da comparação entre os valores médios destes marcadores e a condição da densidade mineral óssea de cada gênero nesta amostra de estudo. Níveis de 25(OH)D foram inversamente proporcionais aos valores de DMO a nível do quadril (r = -0.062 em homens e r = -0.057 em mulheres) e coluna vertebral (r = -0.076 em homens e r = -0.107 em mulheres). Após ajuste dos dados para idade, a correlação negativa não foi mais estatisticamente significante. Níveis séricos de 25(OH)D são inversamente correlacionados com os valores de massa óssea em ambos os gêneros." @default.
• W2315473480 created "2016-06-24" @default.
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• W2315473480 date "2016-07-01" @default.
• W2315473480 modified "2023-09-27" @default.
• W2315473480 title "Vitamin D status and its relationship with bone mineral density in a healthy Iranian population" @default.
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• W2315473480 doi "https://doi.org/10.1016/j.rboe.2015.09.011" @default.
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